STRINGSTRING
PAX6 PAX6 NPHP1 NPHP1 SEPTIN2 SEPTIN2 SHH SHH VCL VCL NPHP1-2 NPHP1-2 OLIG2 OLIG2 FGF4 FGF4 FOXA2 FOXA2 PTCH1 PTCH1 DKK1 DKK1 CTNNB1 CTNNB1 DVL1 DVL1 GLI3 GLI3 WNT5A WNT5A LOX LOX WDPCP WDPCP AXIN2 AXIN2 IFT88 IFT88 SMO SMO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAX6Paired box 6. (486 aa)
NPHP1SH3 domain-containing protein. (690 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
VCLVinculin. (1134 aa)
NPHP1-2Uncharacterized protein. (127 aa)
OLIG2Oligodendrocyte transcription factor 2. (329 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FOXA2Forkhead box A2. (467 aa)
PTCH1Patched 1. (1453 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (262 aa)
CTNNB1Catenin beta 1. (781 aa)
DVL1Dishevelled segment polarity protein 1. (682 aa)
GLI3GLI family zinc finger 3. (1614 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
LOXLysyl oxidase. (418 aa)
WDPCPWD repeat containing planar cell polarity effector. (676 aa)
AXIN2Axin 2. (844 aa)
IFT88Intraflagellar transport 88. (825 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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