STRINGSTRING
PXDN PXDN LOC108633554 LOC108633554 LOC102182848 LOC102182848 LOC108636012 LOC108636012 H3-4 H3-4 LOC108634231 LOC108634231 B2M B2M PSPH PSPH KDM1A KDM1A LOC102180554 LOC102180554 LOC106503499 LOC106503499 LOC108633916 LOC108633916 LOC102171353 LOC102171353 KDM1B KDM1B LOC102169981 LOC102169981 EHMT2 EHMT2 SHMT1 SHMT1 CCNB2 CCNB2 ATF4 ATF4 KDM8 KDM8 CCNB1 CCNB1 CCNA2 CCNA2 PHGDH PHGDH LOC102168547 LOC102168547 ULK1 ULK1 ATG5 ATG5 LOC102189503 LOC102189503 GAPDH GAPDH PSAT1 PSAT1 CDC25C CDC25C LOC102191748 LOC102191748 LOC102185882 LOC102185882 SHMT2 SHMT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PXDNPeroxidasin. (1525 aa)
LOC108633554Histone domain-containing protein. (136 aa)
LOC102182848Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108636012Histone H3; Belongs to the histone H3 family. (136 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108634231Histone H3; Belongs to the histone H3 family. (136 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (124 aa)
PSPHPhosphoserine phosphatase. (225 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (873 aa)
LOC102180554Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106503499Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108633916Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102171353Histone H3; Belongs to the histone H3 family. (136 aa)
KDM1BLysine demethylase 1B. (816 aa)
LOC102169981Histone domain-containing protein. (136 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1268 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
ATF4Activating transcription factor 4. (352 aa)
KDM8Lysine demethylase 8. (406 aa)
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (430 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
LOC102168547Beta-2-microglobulin. (124 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
CDC25CCell division cycle 25C. (452 aa)
LOC102191748Histone domain-containing protein. (136 aa)
LOC102185882Histone H3; Belongs to the histone H3 family. (136 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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