20 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (409 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa)
	PAX1	Paired box 1. (443 aa)
	FOXN1	Forkhead box N1. (645 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	AIRE	Autoimmune regulator. (548 aa)
	PAX9	Paired box 9. (342 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	FOXP3	Forkhead box P3. (463 aa)
	HOXA3	Homeobox A3. (437 aa)
	FOXA2	Forkhead box A2. (467 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	CD4	CD4 molecule. (455 aa)
	CD34	Uncharacterized protein. (384 aa)
	SOX17	SRY-box transcription factor 17. (410 aa)
	CCL25	C-C motif chemokine ligand 25. (150 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIRE	CD4	ENSCHIP00000017845	ENSCHIP00000006662	Autoimmune regulator.	CD4 molecule.	0.817
AIRE	FOXN1	ENSCHIP00000017845	ENSCHIP00000022328	Autoimmune regulator.	Forkhead box N1.	0.873
AIRE	FOXP3	ENSCHIP00000017845	ENSCHIP00000012575	Autoimmune regulator.	Forkhead box P3.	0.625
BMP4	CD34	ENSCHIP00000023678	ENSCHIP00000002645	Bone morphogenetic protein 4.	Uncharacterized protein.	0.672
BMP4	EYA1	ENSCHIP00000023678	ENSCHIP00000025106	Bone morphogenetic protein 4.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.574
BMP4	FGF10	ENSCHIP00000023678	ENSCHIP00000010028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.887
BMP4	FGF2	ENSCHIP00000023678	ENSCHIP00000019134	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.872
BMP4	FGF7	ENSCHIP00000023678	ENSCHIP00000014609	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.707
BMP4	FOXA2	ENSCHIP00000023678	ENSCHIP00000011890	Bone morphogenetic protein 4.	Forkhead box A2.	0.836
BMP4	FOXN1	ENSCHIP00000023678	ENSCHIP00000022328	Bone morphogenetic protein 4.	Forkhead box N1.	0.417
BMP4	GAPDH	ENSCHIP00000023678	ENSCHIP00000025974	Bone morphogenetic protein 4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.761
BMP4	PAX1	ENSCHIP00000023678	ENSCHIP00000030519	Bone morphogenetic protein 4.	Paired box 1.	0.426
BMP4	PAX9	ENSCHIP00000023678	ENSCHIP00000017561	Bone morphogenetic protein 4.	Paired box 9.	0.582
BMP4	SOX17	ENSCHIP00000023678	ENSCHIP00000023300	Bone morphogenetic protein 4.	SRY-box transcription factor 17.	0.876
BMP4	WNT3A	ENSCHIP00000023678	ENSCHIP00000015590	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.874
CCL25	CD4	ENSCHIP00000032082	ENSCHIP00000006662	C-C motif chemokine ligand 25.	CD4 molecule.	0.698
CCL25	FOXN1	ENSCHIP00000032082	ENSCHIP00000022328	C-C motif chemokine ligand 25.	Forkhead box N1.	0.520
CCL25	IFNG	ENSCHIP00000032082	ENSCHIP00000016152	C-C motif chemokine ligand 25.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.451
CD34	BMP4	ENSCHIP00000002645	ENSCHIP00000023678	Uncharacterized protein.	Bone morphogenetic protein 4.	0.672
CD34	CD4	ENSCHIP00000002645	ENSCHIP00000006662	Uncharacterized protein.	CD4 molecule.	0.955