(42 nodes) (2015) Transcriptomic Features of Bovine Blastocysts Derived by Somatic Cell Nuclear Transfer. network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	AIFM2	Apoptosis inducing factor mitochondria associated 2. (373 aa)
	ALDOC	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (493 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (623 aa)
	SOX2	HMG box domain-containing protein. (320 aa)
	LIN28B	Lin-28 homolog B. (255 aa)
	KDM1B	Lysine demethylase 1B. (816 aa)
	NANOG	Homeobox domain-containing protein. (300 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1062 aa)
	KDM3A	Lysine demethylase 3A. (1362 aa)
	KDM5C	Lysine demethylase 5C. (1560 aa)
	RBBP8	RB binding protein 8, endonuclease. (889 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
	HOXB8	Homeobox B8. (243 aa)
	CLIC2	Chloride intracellular channel 2. (247 aa)
	HOXB7	Homeobox B7. (217 aa)
	GCM1	Glial cells missing transcription factor 1. (427 aa)
	CCKBR	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (459 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
	LOC108634721	Tr-type G domain-containing protein. (473 aa)
	TRAF4	TNF receptor-associated factor. (437 aa)
	ALB	Serum albumin. (608 aa)
	SLITRK2	SLIT and NTRK like family member 2. (844 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	TET3	Tet methylcytosine dioxygenase 3. (1640 aa)
	DOK5	Docking protein 5. (322 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	PRELID1	PRELI/MSF1 domain-containing protein. (219 aa)
	POU5F1	POU domain protein. (360 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (735 aa)
	FOXJ3	Forkhead box J3. (628 aa)
	JMJD6	JmjC domain-containing protein. (414 aa)
	ESRRB	Estrogen related receptor beta. (454 aa)
	EPCAM	Epithelial cell adhesion molecule. (314 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	CDX2	Caudal type homeobox 2. (306 aa)
	HOXB4	Homeobox B4. (251 aa)
	MEST	Mesoderm specific transcript. (335 aa)
	HOXB2	Homeobox B2. (354 aa)
	NNAT	Neuronatin. (81 aa)
	KDM6A	Lysine demethylase 6A. (1386 aa)
	LOC102181148	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CCR7	ENSCHIP00000020234	ENSCHIP00000020512	Serum albumin.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.630
ALB	CDX2	ENSCHIP00000020234	ENSCHIP00000029734	Serum albumin.	Caudal type homeobox 2.	0.561
ALB	EPCAM	ENSCHIP00000020234	ENSCHIP00000026828	Serum albumin.	Epithelial cell adhesion molecule.	0.718
ALB	HDAC4	ENSCHIP00000020234	ENSCHIP00000019494	Serum albumin.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.435
ALB	LOC102181148	ENSCHIP00000020234	ENSCHIP00000032981	Serum albumin.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.421
ALB	NANOG	ENSCHIP00000020234	ENSCHIP00000009313	Serum albumin.	Homeobox domain-containing protein.	0.876
ALB	POU5F1	ENSCHIP00000020234	ENSCHIP00000023987	Serum albumin.	POU domain protein.	0.787
ALB	SOX2	ENSCHIP00000020234	ENSCHIP00000007702	Serum albumin.	HMG box domain-containing protein.	0.762
ALB	STAT3	ENSCHIP00000020234	ENSCHIP00000022282	Serum albumin.	Signal transducer and activator of transcription.	0.817
ALDOC	LOC102181148	ENSCHIP00000004951	ENSCHIP00000032981	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.431
CCR7	ALB	ENSCHIP00000020512	ENSCHIP00000020234	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Serum albumin.	0.630
CCR7	STAT3	ENSCHIP00000020512	ENSCHIP00000022282	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Signal transducer and activator of transcription.	0.500
CDX2	ALB	ENSCHIP00000029734	ENSCHIP00000020234	Caudal type homeobox 2.	Serum albumin.	0.561
CDX2	EPCAM	ENSCHIP00000029734	ENSCHIP00000026828	Caudal type homeobox 2.	Epithelial cell adhesion molecule.	0.419
CDX2	ESRRB	ENSCHIP00000029734	ENSCHIP00000026352	Caudal type homeobox 2.	Estrogen related receptor beta.	0.721
CDX2	GCM1	ENSCHIP00000029734	ENSCHIP00000018527	Caudal type homeobox 2.	Glial cells missing transcription factor 1.	0.799
CDX2	NANOG	ENSCHIP00000029734	ENSCHIP00000009313	Caudal type homeobox 2.	Homeobox domain-containing protein.	0.483
CDX2	POU5F1	ENSCHIP00000029734	ENSCHIP00000023987	Caudal type homeobox 2.	POU domain protein.	0.847
CDX2	SOX2	ENSCHIP00000029734	ENSCHIP00000007702	Caudal type homeobox 2.	HMG box domain-containing protein.	0.793
CLIC2	DOK5	ENSCHIP00000016315	ENSCHIP00000021056	Chloride intracellular channel 2.	Docking protein 5.	0.495