18 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	MTHFD1L	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (603 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (665 aa)
	MTHFD2	Uncharacterized protein. (352 aa)
	ALB	Serum albumin. (608 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	PXDN	Peroxidasin. (1525 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	ALDOA	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	ACTB	Uncharacterized protein. (375 aa)
	HK2	Hexokinase 2. (917 aa)
	MTHFD2L	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
	CD4	CD4 molecule. (455 aa)
	PSPH	Phosphoserine phosphatase. (225 aa)
	PKLR	Pyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	ALDOA	ENSCHIP00000011080	ENSCHIP00000011329	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.612
ACTB	CD4	ENSCHIP00000011080	ENSCHIP00000006662	Uncharacterized protein.	CD4 molecule.	0.883
ACTB	HK2	ENSCHIP00000011080	ENSCHIP00000009707	Uncharacterized protein.	Hexokinase 2.	0.728
ACTB	LMNA	ENSCHIP00000011080	ENSCHIP00000026441	Uncharacterized protein.	Lamin A/C; Belongs to the intermediate filament family.	0.847
ACTB	PFKFB3	ENSCHIP00000011080	ENSCHIP00000027532	Uncharacterized protein.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.451
ACTB	PKM	ENSCHIP00000011080	ENSCHIP00000015417	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.744
ACTB	PXDN	ENSCHIP00000011080	ENSCHIP00000015493	Uncharacterized protein.	Peroxidasin.	0.962
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	CD4	ENSCHIP00000020234	ENSCHIP00000006662	Serum albumin.	CD4 molecule.	0.977
ALB	HK2	ENSCHIP00000020234	ENSCHIP00000009707	Serum albumin.	Hexokinase 2.	0.619
ALB	LMNA	ENSCHIP00000020234	ENSCHIP00000026441	Serum albumin.	Lamin A/C; Belongs to the intermediate filament family.	0.667
ALB	PKM	ENSCHIP00000020234	ENSCHIP00000015417	Serum albumin.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.506
ALB	PXDN	ENSCHIP00000020234	ENSCHIP00000015493	Serum albumin.	Peroxidasin.	0.988
ALDOA	ACTB	ENSCHIP00000011329	ENSCHIP00000011080	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Uncharacterized protein.	0.612
ALDOA	HK2	ENSCHIP00000011329	ENSCHIP00000009707	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Hexokinase 2.	0.940
ALDOA	PFKFB3	ENSCHIP00000011329	ENSCHIP00000027532	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.556
ALDOA	PKLR	ENSCHIP00000011329	ENSCHIP00000002740	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.946
ALDOA	PKM	ENSCHIP00000011329	ENSCHIP00000015417	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.971
CD4	ACTB	ENSCHIP00000006662	ENSCHIP00000011080	CD4 molecule.	Uncharacterized protein.	0.883