STRINGSTRING
MTOR MTOR ULK1 ULK1 PHGDH PHGDH SESN1 SESN1 RHEB RHEB ATF4 ATF4 CASP3 CASP3 LAMP2 LAMP2 PSPH PSPH PSAT1 PSAT1 SESN2 SESN2 SESN3 SESN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
SESN1Sestrin 1. (552 aa)
RHEBUncharacterized protein. (187 aa)
ATF4Activating transcription factor 4. (352 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
LAMP2Lysosomal associated membrane protein 2. (494 aa)
PSPHPhosphoserine phosphatase. (225 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
SESN2Sestrin 2. (471 aa)
SESN3Sestrin 3. (492 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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