STRINGSTRING
WRN WRN PCNA PCNA FBH1 FBH1 CCNA2 CCNA2 ATMIN ATMIN GAPDH GAPDH TP53 TP53 RAD50 RAD50 RAD18 RAD18 ACTB ACTB CCNA1 CCNA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WRNWRN RecQ like helicase. (1405 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
FBH1F-box DNA helicase 1. (1048 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (430 aa)
ATMINATM interactor. (821 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
RAD50Zinc-hook domain-containing protein. (1332 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (502 aa)
ACTBUncharacterized protein. (375 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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