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TXNDC5 TXNDC5 BDH1 BDH1 LOC106501717 LOC106501717 LOC102173997 LOC102173997 AIFM2 AIFM2 ACO2 ACO2 ENSCHIP00000004162 ENSCHIP00000004162 EEF1A1 EEF1A1 ATP5F1B ATP5F1B SDHB SDHB ACTB ACTB LMNB2 LMNB2 LMNB1 LMNB1 EEF2 EEF2 CHCHD3 CHCHD3 TPM2 TPM2 FGB FGB UQCRC1 UQCRC1 UQCRFS1 UQCRFS1 UQCRC2 UQCRC2 HSPA8 HSPA8 CKB CKB SDHA SDHA HSP90AB1 HSP90AB1 COL6A2 COL6A2 TUBA1B TUBA1B CKMT1A CKMT1A CKMT2 CKMT2 SUCLG2 SUCLG2 HSPA9 HSPA9 TUFM TUFM ANXA1 ANXA1 GSN GSN TUBB4B TUBB4B EEF1G EEF1G LMNA LMNA NDUFV1 NDUFV1 ETFDH ETFDH TOMM40 TOMM40 SAMM50 SAMM50 NDUFS2 NDUFS2 CKM CKM PDIA3 PDIA3 HSPA5 HSPA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TXNDC5Thioredoxin domain containing 5. (422 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
LOC106501717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC102173997Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (373 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
ENSCHIP00000004162Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (515 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
ACTBUncharacterized protein. (375 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (641 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
EEF2Tr-type G domain-containing protein. (858 aa)
CHCHD3MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (232 aa)
TPM2Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (494 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
CKBCreatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
COL6A2Collagen type VI alpha 2 chain. (1027 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
CKMT1AUncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (416 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (432 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (452 aa)
ANXA1Annexin. (346 aa)
GSNGelsolin. (785 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
EEF1GUncharacterized protein. (440 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
SAMM50SAMM50 sorting and assembly machinery component. (469 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
HSPA5Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family. (655 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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