31 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOCD	Myocardin. (982 aa)
	NOTCH1	Notch receptor 1. (2508 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	CNN1	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
	TCF15	Transcription factor 15. (197 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	ACTA2	Actin alpha 2, smooth muscle. (377 aa)
	KLF4	Kruppel like factor 4. (510 aa)
	MYLK	Myosin light chain kinase. (1887 aa)
	MEOX1	Mesenchyme homeobox 1. (254 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	TAGLN	Transgelin; Belongs to the calponin family. (201 aa)
	GATA5	GATA binding protein 5. (403 aa)
	TSC2	Rap-GAP domain-containing protein. (1817 aa)
	TBX6	T-box transcription factor 6. (437 aa)
	NANOG	Homeobox domain-containing protein. (300 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
	SOX2	HMG box domain-containing protein. (320 aa)
	MYH11	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (518 aa)
	PAX1	Paired box 1. (443 aa)
	CCN2	Cellular communication network factor 2. (349 aa)
	PAX3	Paired box 3. (484 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	POU5F1	POU domain protein. (360 aa)
	FBN1	Fibrillin 1. (2860 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA2	CCN2	ENSCHIP00000018506	ENSCHIP00000030116	Actin alpha 2, smooth muscle.	Cellular communication network factor 2.	0.758
ACTA2	CNN1	ENSCHIP00000018506	ENSCHIP00000021438	Actin alpha 2, smooth muscle.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.849
ACTA2	FBN1	ENSCHIP00000018506	ENSCHIP00000023927	Actin alpha 2, smooth muscle.	Fibrillin 1.	0.573
ACTA2	GAPDH	ENSCHIP00000018506	ENSCHIP00000025974	Actin alpha 2, smooth muscle.	Glyceraldehyde-3-phosphate dehydrogenase.	0.669
ACTA2	KLF4	ENSCHIP00000018506	ENSCHIP00000017278	Actin alpha 2, smooth muscle.	Kruppel like factor 4.	0.480
ACTA2	MYH11	ENSCHIP00000018506	ENSCHIP00000007181	Actin alpha 2, smooth muscle.	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.993
ACTA2	MYLK	ENSCHIP00000018506	ENSCHIP00000015058	Actin alpha 2, smooth muscle.	Myosin light chain kinase.	0.752
ACTA2	MYOCD	ENSCHIP00000018506	ENSCHIP00000023758	Actin alpha 2, smooth muscle.	Myocardin.	0.737
ACTA2	SMAD2	ENSCHIP00000018506	ENSCHIP00000022106	Actin alpha 2, smooth muscle.	Mothers against decapentaplegic homolog.	0.427
ACTA2	SOX9	ENSCHIP00000018506	ENSCHIP00000024523	Actin alpha 2, smooth muscle.	SRY-box transcription factor 9.	0.563
ACTA2	TAGLN	ENSCHIP00000018506	ENSCHIP00000013286	Actin alpha 2, smooth muscle.	Transgelin; Belongs to the calponin family.	0.933
ACTA2	TGFBR2	ENSCHIP00000018506	ENSCHIP00000008226	Actin alpha 2, smooth muscle.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.456
AKT2	GAPDH	ENSCHIP00000013931	ENSCHIP00000025974	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.703
AKT2	MTOR	ENSCHIP00000013931	ENSCHIP00000021872	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.980
AKT2	NOTCH1	ENSCHIP00000013931	ENSCHIP00000023681	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Notch receptor 1.	0.447
AKT2	RPS6KB1	ENSCHIP00000013931	ENSCHIP00000002789	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.603
AKT2	SMAD2	ENSCHIP00000013931	ENSCHIP00000022106	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.478
AKT2	TSC2	ENSCHIP00000013931	ENSCHIP00000012677	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Rap-GAP domain-containing protein.	0.925
BMP4	CCN2	ENSCHIP00000023678	ENSCHIP00000030116	Bone morphogenetic protein 4.	Cellular communication network factor 2.	0.707
BMP4	FBN1	ENSCHIP00000023678	ENSCHIP00000023927	Bone morphogenetic protein 4.	Fibrillin 1.	0.543