31 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MMP8	Matrix metallopeptidase 8. (470 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1608 aa)
	LOC102174895	Uncharacterized protein. (735 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	COL14A1	Collagen type XIV alpha 1 chain. (1775 aa)
	AHSG	Alpha 2-HS glycoprotein. (359 aa)
	COL1A2	Collagen type I alpha 2 chain. (1128 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	BGLAP	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (97 aa)
	SP7	Sp7 transcription factor. (431 aa)
	MEPE	Matrix extracellular phosphoglycoprotein. (501 aa)
	SERPINH1	Serpin family H member 1; Belongs to the serpin family. (418 aa)
	PHEX	Phosphate regulating endopeptidase homolog X-linked. (686 aa)
	ENSCHIP00000004646	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (124 aa)
	LOC102176799	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase. (385 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	GDF10	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (478 aa)
	LOC102181016	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
	BMP2	TGF_BETA_2 domain-containing protein. (381 aa)
	ACTB	Uncharacterized protein. (375 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (316 aa)
	RUNX2	RUNX family transcription factor 2. (585 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	DNASE1	Deoxyribonuclease; Belongs to the DNase I family. (282 aa)
	LOC102168547	Beta-2-microglobulin. (124 aa)
	SOST	Sclerostin. (212 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	B2M	ENSCHIP00000011080	ENSCHIP00000004681	Uncharacterized protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.870
ACTB	BGLAP	ENSCHIP00000011080	ENSCHIP00000031297	Uncharacterized protein.	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	0.696
ACTB	BMP2	ENSCHIP00000011080	ENSCHIP00000010414	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.657
ACTB	BMP4	ENSCHIP00000011080	ENSCHIP00000023678	Uncharacterized protein.	Bone morphogenetic protein 4.	0.697
ACTB	BMP7	ENSCHIP00000011080	ENSCHIP00000006043	Uncharacterized protein.	Bone morphogenetic protein 7.	0.547
ACTB	BMPR2	ENSCHIP00000011080	ENSCHIP00000022191	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.452
ACTB	COL1A1	ENSCHIP00000011080	ENSCHIP00000023918	Uncharacterized protein.	Collagen type I alpha 1 chain.	0.776
ACTB	COL1A2	ENSCHIP00000011080	ENSCHIP00000031191	Uncharacterized protein.	Collagen type I alpha 2 chain.	0.563
ACTB	ENSCHIP00000004646	ENSCHIP00000011080	ENSCHIP00000004646	Uncharacterized protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.804
ACTB	ESR1	ENSCHIP00000011080	ENSCHIP00000012243	Uncharacterized protein.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.859
ACTB	FGF2	ENSCHIP00000011080	ENSCHIP00000019134	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.763
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	GAPDHS	ENSCHIP00000011080	ENSCHIP00000005676	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.911
ACTB	LOC102168547	ENSCHIP00000011080	ENSCHIP00000020182	Uncharacterized protein.	Beta-2-microglobulin.	0.870
ACTB	LOC102174895	ENSCHIP00000011080	ENSCHIP00000024875	Uncharacterized protein.	Uncharacterized protein.	0.776
ACTB	LOC102176799	ENSCHIP00000011080	ENSCHIP00000004827	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.937
ACTB	LOC102181016	ENSCHIP00000011080	ENSCHIP00000010405	Uncharacterized protein.	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.917
ACTB	RUNX2	ENSCHIP00000011080	ENSCHIP00000015454	Uncharacterized protein.	RUNX family transcription factor 2.	0.834
ACTB	SOST	ENSCHIP00000011080	ENSCHIP00000021643	Uncharacterized protein.	Sclerostin.	0.530
ACTB	SP7	ENSCHIP00000011080	ENSCHIP00000033356	Uncharacterized protein.	Sp7 transcription factor.	0.409