STRINGSTRING
CD82 CD82 RPS24 RPS24 CDK1 CDK1 KIF23 KIF23 TMEM54 TMEM54 EIF3E EIF3E PTEN PTEN CD9 CD9 CD81 CD81 RACGAP1 RACGAP1 EEF1A1 EEF1A1 LOC108633249 LOC108633249 RPLP1 RPLP1 INS INS EEF1D EEF1D SH3D19 SH3D19 CDK6 CDK6 RPS3 RPS3 TMEM126B TMEM126B LOC102172503 LOC102172503 TSG101 TSG101 BCL7C BCL7C TMEM134 TMEM134 GOLT1A GOLT1A EEF2 EEF2 MRPL52 MRPL52 C1orf122 C1orf122 MLF2 MLF2 ELOC ELOC ELOB ELOB RPLP0 RPLP0 CCNB1 CCNB1 LRRC75A LRRC75A SERF2 SERF2 RPS29 RPS29 RPL18 RPL18 DLGAP1 DLGAP1 SCARB1 SCARB1 RO60 RO60 ZNFX1 ZNFX1 RIPK2 RIPK2 EIF3F EIF3F LRBA LRBA GTF3A GTF3A CD63 CD63 HNRNPH1 HNRNPH1 EEA1 EEA1 CD44 CD44 MIPEP MIPEP RAB13 RAB13 HNRNPA2B1 HNRNPA2B1 EEF1G EEF1G GAPDH GAPDH EIF3F-2 EIF3F-2 RPL12 RPL12 EPCAM EPCAM EIF3K EIF3K RPL31 RPL31 GTF3C5 GTF3C5 FTL FTL TP53 TP53 HNRNPA1 HNRNPA1 RPL28 RPL28 PROM1 PROM1 ENSCHIP00000032327 ENSCHIP00000032327 OSGIN2 OSGIN2 EEF1B2 EEF1B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD82Tetraspanin. (265 aa)
RPS2440S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (143 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (312 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa)
TMEM54Transmembrane protein 54. (226 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
CD9Tetraspanin. (226 aa)
CD81Tetraspanin. (236 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
LOC108633249Uncharacterized protein. (103 aa)
RPLP1Ribosomal protein lateral stalk subunit P1. (114 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
EEF1DUncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (280 aa)
SH3D19SH3 domain containing 19. (1043 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
TMEM126BTransmembrane protein 126B. (230 aa)
LOC102172503Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
TSG101Uncharacterized protein. (391 aa)
BCL7CBAF chromatin remodeling complex subunit BCL7C. (217 aa)
TMEM134Transmembrane protein 134. (190 aa)
GOLT1AGolgi transport 1A. (132 aa)
EEF2Tr-type G domain-containing protein. (858 aa)
MRPL52Mitochondrial ribosomal protein L52. (124 aa)
C1orf122Chromosome 1 open reading frame 122. (158 aa)
MLF2Myeloid leukemia factor 2. (247 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
ELOBUbiquitin-like domain-containing protein. (118 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (318 aa)
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa)
LRRC75ALeucine rich repeat containing 75A. (345 aa)
SERF2Small EDRK-rich factor 2; Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity). Induces conformational changes in amyloid proteins, such as HTT, driving them into compact formations preceding the formation of aggregates (By similarity). (59 aa)
RPS29Uncharacterized protein. (64 aa)
RPL18Ribosomal protein L18. (187 aa)
DLGAP1DLG associated protein 1. (987 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
RO60Ro60, Y RNA binding protein. (538 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
LRBALPS responsive beige-like anchor protein. (2853 aa)
GTF3AUncharacterized protein. (422 aa)
CD63Tetraspanin. (237 aa)
HNRNPH1Heterogeneous nuclear ribonucleoprotein H1. (463 aa)
EEA1Early endosome antigen 1. (1452 aa)
CD44CD44 molecule (Indian blood group). (715 aa)
MIPEPMitochondrial intermediate peptidase. (707 aa)
RAB13Uncharacterized protein. (203 aa)
HNRNPA2B1Heterogeneous nuclear ribonucleoprotein A2/B1. (353 aa)
EEF1GUncharacterized protein. (440 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
EIF3F-2Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (334 aa)
RPL12Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family. (216 aa)
EPCAMEpithelial cell adhesion molecule. (314 aa)
EIF3KEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa)
RPL31Uncharacterized protein. (125 aa)
GTF3C5General transcription factor IIIC subunit 5. (537 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
HNRNPA1Uncharacterized protein. (320 aa)
RPL28Ribosomal_L28e domain-containing protein. (137 aa)
PROM1Prominin 1. (855 aa)
ENSCHIP00000032327Uncharacterized protein. (105 aa)
OSGIN2Oxidative stress induced growth inhibitor family member 2. (550 aa)
EEF1B2Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (225 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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