9 items (Capra hircus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	REV3L	REV3 like, DNA directed polymerase zeta catalytic subunit. (3134 aa)
	RNASEH1	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (285 aa)
	CDC27	Cell division cycle 27. (824 aa)
	ALB	Serum albumin. (608 aa)
	POLD1	DNA polymerase. (1115 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	ACTB	Uncharacterized protein. (375 aa)
	TOP1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	TOP1	ENSCHIP00000011080	ENSCHIP00000028689	Uncharacterized protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.516
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961
ALB	TOP1	ENSCHIP00000020234	ENSCHIP00000028689	Serum albumin.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.407
CDC27	POLD1	ENSCHIP00000021697	ENSCHIP00000019836	Cell division cycle 27.	DNA polymerase.	0.573
PCNA	POLD1	ENSCHIP00000015091	ENSCHIP00000019836	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.990
PCNA	POLD2	ENSCHIP00000015091	ENSCHIP00000005641	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase delta 2, accessory subunit.	0.989
PCNA	REV3L	ENSCHIP00000015091	ENSCHIP00000026893	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.948
PCNA	TOP1	ENSCHIP00000015091	ENSCHIP00000028689	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.475
POLD1	CDC27	ENSCHIP00000019836	ENSCHIP00000021697	DNA polymerase.	Cell division cycle 27.	0.573
POLD1	PCNA	ENSCHIP00000019836	ENSCHIP00000015091	DNA polymerase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
POLD1	POLD2	ENSCHIP00000019836	ENSCHIP00000005641	DNA polymerase.	DNA polymerase delta 2, accessory subunit.	0.999
POLD1	REV3L	ENSCHIP00000019836	ENSCHIP00000026893	DNA polymerase.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.856
POLD1	TOP1	ENSCHIP00000019836	ENSCHIP00000028689	DNA polymerase.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.583
POLD2	PCNA	ENSCHIP00000005641	ENSCHIP00000015091	DNA polymerase delta 2, accessory subunit.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.989
POLD2	POLD1	ENSCHIP00000005641	ENSCHIP00000019836	DNA polymerase delta 2, accessory subunit.	DNA polymerase.	0.999
POLD2	REV3L	ENSCHIP00000005641	ENSCHIP00000026893	DNA polymerase delta 2, accessory subunit.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.993
REV3L	PCNA	ENSCHIP00000026893	ENSCHIP00000015091	REV3 like, DNA directed polymerase zeta catalytic subunit.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.948
REV3L	POLD1	ENSCHIP00000026893	ENSCHIP00000019836	REV3 like, DNA directed polymerase zeta catalytic subunit.	DNA polymerase.	0.856
REV3L	POLD2	ENSCHIP00000026893	ENSCHIP00000005641	REV3 like, DNA directed polymerase zeta catalytic subunit.	DNA polymerase delta 2, accessory subunit.	0.993