node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AR | ESR1 | ENSCHIP00000024342 | ENSCHIP00000012243 | Androgen receptor. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.767 |
AR | FOXA1 | ENSCHIP00000024342 | ENSCHIP00000027706 | Androgen receptor. | Forkhead box A1. | 0.935 |
AR | LEP | ENSCHIP00000024342 | ENSCHIP00000021235 | Androgen receptor. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.863 |
AR | PGR | ENSCHIP00000024342 | ENSCHIP00000024658 | Androgen receptor. | Progesterone receptor. | 0.643 |
ESR1 | AR | ENSCHIP00000012243 | ENSCHIP00000024342 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Androgen receptor. | 0.767 |
ESR1 | FOXA1 | ENSCHIP00000012243 | ENSCHIP00000027706 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Forkhead box A1. | 0.939 |
ESR1 | LEP | ENSCHIP00000012243 | ENSCHIP00000021235 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.917 |
ESR1 | PGR | ENSCHIP00000012243 | ENSCHIP00000024658 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Progesterone receptor. | 0.976 |
FOXA1 | AR | ENSCHIP00000027706 | ENSCHIP00000024342 | Forkhead box A1. | Androgen receptor. | 0.935 |
FOXA1 | ESR1 | ENSCHIP00000027706 | ENSCHIP00000012243 | Forkhead box A1. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.939 |
FOXA1 | LEP | ENSCHIP00000027706 | ENSCHIP00000021235 | Forkhead box A1. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.566 |
FOXA1 | PGR | ENSCHIP00000027706 | ENSCHIP00000024658 | Forkhead box A1. | Progesterone receptor. | 0.846 |
LEP | AR | ENSCHIP00000021235 | ENSCHIP00000024342 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | Androgen receptor. | 0.863 |
LEP | ESR1 | ENSCHIP00000021235 | ENSCHIP00000012243 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.917 |
LEP | FOXA1 | ENSCHIP00000021235 | ENSCHIP00000027706 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | Forkhead box A1. | 0.566 |
LEP | PGR | ENSCHIP00000021235 | ENSCHIP00000024658 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | Progesterone receptor. | 0.912 |
PGR | AR | ENSCHIP00000024658 | ENSCHIP00000024342 | Progesterone receptor. | Androgen receptor. | 0.643 |
PGR | ESR1 | ENSCHIP00000024658 | ENSCHIP00000012243 | Progesterone receptor. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.976 |
PGR | FOXA1 | ENSCHIP00000024658 | ENSCHIP00000027706 | Progesterone receptor. | Forkhead box A1. | 0.846 |
PGR | LEP | ENSCHIP00000024658 | ENSCHIP00000021235 | Progesterone receptor. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.912 |