79 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	PFKL	Phosphofructokinase, liver type. (803 aa)
	FAM162A	Family with sequence similarity 162 member A. (154 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
	OCA2	OCA2 melanosomal transmembrane protein. (838 aa)
	PLOD1	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (724 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1510 aa)
	FMOD	Fibromodulin. (376 aa)
	MRPL54	Mitochondrial ribosomal protein L54. (138 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1179 aa)
	PRELID2	PRELI domain containing 2. (177 aa)
	BNIP3L	Uncharacterized protein. (227 aa)
	MREG	Melanoregulin. (214 aa)
	IGFBP3	Uncharacterized protein. (293 aa)
	XBP1	BZIP domain-containing protein. (261 aa)
	ALOXE3	Arachidonate lipoxygenase 3. (711 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	PGAM1	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	UNC5A	Unc-5 netrin receptor A. (902 aa)
	ADM	Adrenomedullin. (189 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	JMJD6	JmjC domain-containing protein. (414 aa)
	GPC6	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (297 aa)
	MTHFD2	Uncharacterized protein. (352 aa)
	SLC1A5	Amino acid transporter. (530 aa)
	MCM3	DNA helicase; Belongs to the MCM family. (808 aa)
	TRIB3	Tribbles pseudokinase 3. (357 aa)
	KDM5B	Lysine demethylase 5B. (1539 aa)
	SLC7A5	Solute carrier family 7 member 5. (505 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (774 aa)
	LDH-A	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
	PLOD2	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (760 aa)
	MCM4	DNA helicase; Belongs to the MCM family. (851 aa)
	MCM6	DNA helicase; Belongs to the MCM family. (821 aa)
	KDM6B	Lysine demethylase 6B. (1685 aa)
	AGTRAP	Angiotensin II receptor associated protein. (155 aa)
	EPAS1	Endothelial PAS domain protein 1. (898 aa)
	BNIP3	BCL2 interacting protein 3. (193 aa)
	E2F4	E2F transcription factor 4. (405 aa)
	SAP30	Sin3A associated protein 30. (220 aa)
	E2F6	E2F transcription factor 6. (288 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (397 aa)
	CHAF1B	Chromatin assembly factor 1 subunit B. (567 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	PLOD3	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (751 aa)
	LOXL2	Lysyl oxidase like 2. (791 aa)
	MXI1	MAX interactor 1, dimerization protein. (291 aa)
	BHLHE40	Basic helix-loop-helix family member e40. (412 aa)
	ZNF292	Zinc finger protein 292. (2680 aa)
	TBX2	T-box transcription factor 2. (771 aa)
	P4HA1	Prolyl 4-hydroxylase subunit alpha 1. (534 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	ATRX	ATRX chromatin remodeler. (2105 aa)
	NAMPT	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
	ACTB	Uncharacterized protein. (375 aa)
	EXO1	Exonuclease 1. (835 aa)
	KDM3A	Lysine demethylase 3A. (1362 aa)
	KLF12	Kruppel-like factor 12. (402 aa)
	SLC24A5	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (501 aa)
	SLC16A3	Solute carrier family 16 member 3. (461 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (768 aa)
	SLC2A3	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	DTWD1	DTW domain containing 1. (301 aa)
	MCM5	DNA helicase; Belongs to the MCM family. (734 aa)
	ZNF524	Zinc finger protein 524. (265 aa)
	DARS1	Aspartyl-tRNA synthetase. (501 aa)
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (116 aa)
	UNC13A	Unc-13 homolog A. (1730 aa)
	NF1	Neurofibromin 1. (2848 aa)
	RRM2	Ribonucleotide reductase regulatory subunit M2. (389 aa)
	PGK1	Phosphoglycerate kinase. (424 aa)
	CDC6	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (562 aa)
	POSTN	Periostin. (836 aa)
	RAB27A	RAB27A, member RAS oncogene family. (221 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	SEH1L	SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (422 aa)
	TNFSF9	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (252 aa)
	FANCA	FA complementation group A. (1416 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ATRX	ENSCHIP00000011080	ENSCHIP00000011584	Uncharacterized protein.	ATRX chromatin remodeler.	0.444
ACTB	BNIP3	ENSCHIP00000011080	ENSCHIP00000016664	Uncharacterized protein.	BCL2 interacting protein 3.	0.659
ACTB	BRAF	ENSCHIP00000011080	ENSCHIP00000019379	Uncharacterized protein.	B-Raf proto-oncogene, serine/threonine kinase.	0.746
ACTB	CDC6	ENSCHIP00000011080	ENSCHIP00000005199	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.411
ACTB	CXCL12	ENSCHIP00000011080	ENSCHIP00000007530	Uncharacterized protein.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.678
ACTB	EXO1	ENSCHIP00000011080	ENSCHIP00000010493	Uncharacterized protein.	Exonuclease 1.	0.400
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	IGFBP3	ENSCHIP00000011080	ENSCHIP00000029037	Uncharacterized protein.	Uncharacterized protein.	0.537
ACTB	ITGA2	ENSCHIP00000011080	ENSCHIP00000032957	Uncharacterized protein.	Integrin subunit alpha 2; Belongs to the integrin alpha chain family.	0.952
ACTB	KDM3A	ENSCHIP00000011080	ENSCHIP00000010327	Uncharacterized protein.	Lysine demethylase 3A.	0.726
ACTB	KDM6B	ENSCHIP00000011080	ENSCHIP00000017411	Uncharacterized protein.	Lysine demethylase 6B.	0.446
ACTB	LDH-A	ENSCHIP00000011080	ENSCHIP00000019303	Uncharacterized protein.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.843
ACTB	NAMPT	ENSCHIP00000011080	ENSCHIP00000011406	Uncharacterized protein.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.509
ACTB	NF1	ENSCHIP00000011080	ENSCHIP00000007274	Uncharacterized protein.	Neurofibromin 1.	0.472
ACTB	NRAS	ENSCHIP00000011080	ENSCHIP00000027121	Uncharacterized protein.	NRAS proto-oncogene, GTPase.	0.655
ACTB	P4HA1	ENSCHIP00000011080	ENSCHIP00000012099	Uncharacterized protein.	Prolyl 4-hydroxylase subunit alpha 1.	0.420
ACTB	PFKL	ENSCHIP00000011080	ENSCHIP00000000566	Uncharacterized protein.	Phosphofructokinase, liver type.	0.523
ACTB	PFKP	ENSCHIP00000011080	ENSCHIP00000030216	Uncharacterized protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.663
ACTB	PGK1	ENSCHIP00000011080	ENSCHIP00000005700	Uncharacterized protein.	Phosphoglycerate kinase.	0.778
ACTB	PKM	ENSCHIP00000011080	ENSCHIP00000015417	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.744