STRINGSTRING
GAPDH GAPDH SQSTM1 SQSTM1 ATG12 ATG12 WIPI2 WIPI2 PXDN PXDN ATG14 ATG14 GABARAPL2 GABARAPL2 PIK3C3 PIK3C3 PARK2 PARK2 MAP1A MAP1A ATG101 ATG101 ATP6V0D1 ATP6V0D1 MAP1S MAP1S RB1CC1 RB1CC1 ULK1 ULK1 ALB ALB ATG5 ATG5 LAMP1 LAMP1 CDSN CDSN INS INS LGALS3 LGALS3 ZFYVE1 ZFYVE1 ATG3 ATG3 MAP1B MAP1B ATG13 ATG13 ATG16L1 ATG16L1 BECN1 BECN1 MTOR MTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
SQSTM1Sequestosome 1. (440 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (436 aa)
PXDNPeroxidasin. (1525 aa)
ATG14Autophagy related 14. (492 aa)
GABARAPL2Uncharacterized protein. (117 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
PARK2Ubiquitin-like domain-containing protein. (293 aa)
MAP1AMicrotubule associated protein 1A. (3098 aa)
ATG101Autophagy related 101. (218 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
MAP1SMicrotubule associated protein 1S. (1066 aa)
RB1CC1RB1 inducible coiled-coil 1. (1589 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
ALBSerum albumin. (608 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LAMP1Lysosomal associated membrane protein 1. (409 aa)
CDSNCorneodesmosin. (484 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
LGALS3Galectin. (260 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (789 aa)
ATG3Uncharacterized protein. (158 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (517 aa)
ATG16L1Autophagy related 16 like 1. (607 aa)
BECN1Uncharacterized protein. (448 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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