STRINGSTRING
CTNNB1 CTNNB1 H3-4 H3-4 LOC108634231 LOC108634231 HDAC6 HDAC6 LOC102180554 LOC102180554 LOC106503499 LOC106503499 LOC108633916 LOC108633916 HDAC11 HDAC11 ENTPD2 ENTPD2 SIRT1 SIRT1 LOC102171353 LOC102171353 LOC102169981 LOC102169981 TXN TXN SIRT3 SIRT3 SIRT7 SIRT7 HDAC10 HDAC10 SIRT5 SIRT5 HDAC4 HDAC4 ALB ALB HDAC8 HDAC8 SIRT2 SIRT2 HDAC1 HDAC1 LOC102189503 LOC102189503 HDAC3 HDAC3 HDAC2 HDAC2 CTTN CTTN LOC102191748 LOC102191748 LOC102185882 LOC102185882 LOC108633554 LOC108633554 LOC102182848 LOC102182848 LOC108636012 LOC108636012
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNB1Catenin beta 1. (781 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108634231Histone H3; Belongs to the histone H3 family. (136 aa)
HDAC6Histone deacetylase 6. (988 aa)
LOC102180554Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106503499Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108633916Histone H3; Belongs to the histone H3 family. (136 aa)
HDAC11Histone deacetylase 11. (349 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
LOC102171353Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102169981Histone domain-containing protein. (136 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (333 aa)
SIRT7Sirtuin 7. (405 aa)
HDAC10Histone deacetylase 10. (672 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
ALBSerum albumin. (608 aa)
HDAC8Hist_deacetyl domain-containing protein. (215 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (464 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
CTTNCortactin. (554 aa)
LOC102191748Histone domain-containing protein. (136 aa)
LOC102185882Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108633554Histone domain-containing protein. (136 aa)
LOC102182848Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108636012Histone H3; Belongs to the histone H3 family. (136 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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