STRINGSTRING
GABARAPL2 GABARAPL2 ULK2 ULK2 ATG3 ATG3 MAP1B MAP1B PIK3C3 PIK3C3 ATG14 ATG14 MAP1A MAP1A IFNG IFNG ATG4B ATG4B ATG7 ATG7 ULK1 ULK1 ATG5 ATG5 MAP1S MAP1S LOC102170144 LOC102170144 GABARAP GABARAP GBP2 GBP2 ATG12 ATG12 GABARAPL1 GABARAPL1 ATG16L1 ATG16L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GABARAPL2Uncharacterized protein. (117 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1035 aa)
ATG3Uncharacterized protein. (158 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
ATG14Autophagy related 14. (492 aa)
MAP1AMicrotubule associated protein 1A. (3098 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (376 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (722 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
MAP1SMicrotubule associated protein 1S. (1066 aa)
LOC102170144GB1/RHD3-type G domain-containing protein. (593 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
GBP2Guanylate binding protein 2. (508 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
GABARAPL1GABA type A receptor associated protein like 1. (117 aa)
ATG16L1Autophagy related 16 like 1. (607 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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