11 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TUBE1	Tubulin epsilon 1; Belongs to the tubulin family. (475 aa)
	PTK6	Tyrosine-protein kinase. (450 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
	CTTN	Cortactin. (554 aa)
	ARHGEF5	DH domain-containing protein. (449 aa)
	SRC	Tyrosine-protein kinase. (538 aa)
	STAP2	Signal transducing adaptor family member 2. (423 aa)
	SHC1	SHC adaptor protein 1. (583 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	EGFR	Receptor protein-tyrosine kinase. (1208 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF5	GRB2	ENSCHIP00000000980	ENSCHIP00000015407	DH domain-containing protein.	Growth factor receptor bound protein 2.	0.418
ARHGEF5	PTK6	ENSCHIP00000000980	ENSCHIP00000030615	DH domain-containing protein.	Tyrosine-protein kinase.	0.471
ARHGEF5	SRC	ENSCHIP00000000980	ENSCHIP00000002619	DH domain-containing protein.	Tyrosine-protein kinase.	0.411
ARHGEF5	STAP2	ENSCHIP00000000980	ENSCHIP00000007105	DH domain-containing protein.	Signal transducing adaptor family member 2.	0.538
CTTN	DNM2	ENSCHIP00000033179	ENSCHIP00000031761	Cortactin.	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.979
CTTN	EGFR	ENSCHIP00000033179	ENSCHIP00000022759	Cortactin.	Receptor protein-tyrosine kinase.	0.661
CTTN	GRB2	ENSCHIP00000033179	ENSCHIP00000015407	Cortactin.	Growth factor receptor bound protein 2.	0.732
CTTN	SRC	ENSCHIP00000033179	ENSCHIP00000002619	Cortactin.	Tyrosine-protein kinase.	0.935
DNM2	CTTN	ENSCHIP00000031761	ENSCHIP00000033179	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Cortactin.	0.979
DNM2	GRB2	ENSCHIP00000031761	ENSCHIP00000015407	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Growth factor receptor bound protein 2.	0.701
DNM2	SRC	ENSCHIP00000031761	ENSCHIP00000002619	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Tyrosine-protein kinase.	0.744
EGFR	CTTN	ENSCHIP00000022759	ENSCHIP00000033179	Receptor protein-tyrosine kinase.	Cortactin.	0.661
EGFR	GRB2	ENSCHIP00000022759	ENSCHIP00000015407	Receptor protein-tyrosine kinase.	Growth factor receptor bound protein 2.	0.999
EGFR	PTK6	ENSCHIP00000022759	ENSCHIP00000030615	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.554
EGFR	PTPN11	ENSCHIP00000022759	ENSCHIP00000020822	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.997
EGFR	SHC1	ENSCHIP00000022759	ENSCHIP00000010307	Receptor protein-tyrosine kinase.	SHC adaptor protein 1.	0.996
EGFR	SRC	ENSCHIP00000022759	ENSCHIP00000002619	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.948
GRB2	ARHGEF5	ENSCHIP00000015407	ENSCHIP00000000980	Growth factor receptor bound protein 2.	DH domain-containing protein.	0.418
GRB2	CTTN	ENSCHIP00000015407	ENSCHIP00000033179	Growth factor receptor bound protein 2.	Cortactin.	0.732
GRB2	DNM2	ENSCHIP00000015407	ENSCHIP00000031761	Growth factor receptor bound protein 2.	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.701