7 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	CD36	Uncharacterized protein; Belongs to the CD36 family. (472 aa)
	NONO	Non-POU domain containing octamer binding. (470 aa)
	TNF	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
	ACTB	Uncharacterized protein. (375 aa)
	PSPC1	Paraspeckle component 1. (520 aa)
	SFPQ	Splicing factor proline and glutamine rich. (711 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CD36	ENSCHIP00000011080	ENSCHIP00000030240	Uncharacterized protein.	Uncharacterized protein; Belongs to the CD36 family.	0.734
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	NONO	ENSCHIP00000011080	ENSCHIP00000000521	Uncharacterized protein.	Non-POU domain containing octamer binding.	0.402
ACTB	TNF	ENSCHIP00000011080	ENSCHIP00000004561	Uncharacterized protein.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.886
CD36	ACTB	ENSCHIP00000030240	ENSCHIP00000011080	Uncharacterized protein; Belongs to the CD36 family.	Uncharacterized protein.	0.734
CD36	GAPDH	ENSCHIP00000030240	ENSCHIP00000025974	Uncharacterized protein; Belongs to the CD36 family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.711
CD36	TNF	ENSCHIP00000030240	ENSCHIP00000004561	Uncharacterized protein; Belongs to the CD36 family.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.714
GAPDH	ACTB	ENSCHIP00000025974	ENSCHIP00000011080	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.979
GAPDH	CD36	ENSCHIP00000025974	ENSCHIP00000030240	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein; Belongs to the CD36 family.	0.711
GAPDH	SFPQ	ENSCHIP00000025974	ENSCHIP00000026986	Glyceraldehyde-3-phosphate dehydrogenase.	Splicing factor proline and glutamine rich.	0.420
GAPDH	TNF	ENSCHIP00000025974	ENSCHIP00000004561	Glyceraldehyde-3-phosphate dehydrogenase.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.915
NONO	ACTB	ENSCHIP00000000521	ENSCHIP00000011080	Non-POU domain containing octamer binding.	Uncharacterized protein.	0.402
NONO	PSPC1	ENSCHIP00000000521	ENSCHIP00000016458	Non-POU domain containing octamer binding.	Paraspeckle component 1.	0.855
NONO	SFPQ	ENSCHIP00000000521	ENSCHIP00000026986	Non-POU domain containing octamer binding.	Splicing factor proline and glutamine rich.	0.967
PSPC1	NONO	ENSCHIP00000016458	ENSCHIP00000000521	Paraspeckle component 1.	Non-POU domain containing octamer binding.	0.855
PSPC1	SFPQ	ENSCHIP00000016458	ENSCHIP00000026986	Paraspeckle component 1.	Splicing factor proline and glutamine rich.	0.803
SFPQ	GAPDH	ENSCHIP00000026986	ENSCHIP00000025974	Splicing factor proline and glutamine rich.	Glyceraldehyde-3-phosphate dehydrogenase.	0.420
SFPQ	NONO	ENSCHIP00000026986	ENSCHIP00000000521	Splicing factor proline and glutamine rich.	Non-POU domain containing octamer binding.	0.967
SFPQ	PSPC1	ENSCHIP00000026986	ENSCHIP00000016458	Splicing factor proline and glutamine rich.	Paraspeckle component 1.	0.803
TNF	ACTB	ENSCHIP00000004561	ENSCHIP00000011080	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	Uncharacterized protein.	0.886