23 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NUAK1	NUAK family kinase 1. (662 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	COL1A2	Collagen type I alpha 2 chain. (1128 aa)
	MMP7	Matrix metallopeptidase 7. (276 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	CDK6	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	SQOR	Pyr_redox_2 domain-containing protein. (450 aa)
	COL5A2	Collagen type V alpha 2 chain. (1252 aa)
	CPT2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	TST	Sulfurtransferase. (297 aa)
	BNIP3	BCL2 interacting protein 3. (193 aa)
	MMP9	Uncharacterized protein. (709 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1591 aa)
	COL12A1	Collagen type XII alpha 1 chain. (3046 aa)
	LASP1	LIM and SH3 protein 1. (260 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (682 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1608 aa)
	SRCIN1	SRC kinase signaling inhibitor 1. (1246 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	RCC2	Regulator of chromosome condensation 2. (520 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACOX1	ENSCHIP00000006718	ENSCHIP00000024456	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.951
ACAA1	CPT2	ENSCHIP00000006718	ENSCHIP00000012047	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.	0.771
ACAA1	HMGCS2	ENSCHIP00000006718	ENSCHIP00000031203	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.986
ACOX1	ACAA1	ENSCHIP00000024456	ENSCHIP00000006718	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.951
ACOX1	CPT2	ENSCHIP00000024456	ENSCHIP00000012047	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.	0.852
ACOX1	GAPDH	ENSCHIP00000024456	ENSCHIP00000025974	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.480
ACOX1	HMGCS2	ENSCHIP00000024456	ENSCHIP00000031203	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.655
ACOX1	INS	ENSCHIP00000024456	ENSCHIP00000007610	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.598
BNIP3	GAPDH	ENSCHIP00000016664	ENSCHIP00000025974	BCL2 interacting protein 3.	Glyceraldehyde-3-phosphate dehydrogenase.	0.617
CDK6	GAPDH	ENSCHIP00000008415	ENSCHIP00000025974	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.782
CDK6	INS	ENSCHIP00000008415	ENSCHIP00000007610	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.426
CDK6	MMP9	ENSCHIP00000008415	ENSCHIP00000016938	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.514
COL12A1	COL1A1	ENSCHIP00000020533	ENSCHIP00000023918	Collagen type XII alpha 1 chain.	Collagen type I alpha 1 chain.	0.577
COL12A1	COL1A2	ENSCHIP00000020533	ENSCHIP00000031191	Collagen type XII alpha 1 chain.	Collagen type I alpha 2 chain.	0.698
COL12A1	COL4A1	ENSCHIP00000020533	ENSCHIP00000025370	Collagen type XII alpha 1 chain.	Collagen type IV alpha 1 chain.	0.491
COL12A1	COL5A2	ENSCHIP00000020533	ENSCHIP00000009695	Collagen type XII alpha 1 chain.	Collagen type V alpha 2 chain.	0.661
COL1A1	COL12A1	ENSCHIP00000023918	ENSCHIP00000020533	Collagen type I alpha 1 chain.	Collagen type XII alpha 1 chain.	0.577
COL1A1	COL1A2	ENSCHIP00000023918	ENSCHIP00000031191	Collagen type I alpha 1 chain.	Collagen type I alpha 2 chain.	0.999
COL1A1	COL4A1	ENSCHIP00000023918	ENSCHIP00000025370	Collagen type I alpha 1 chain.	Collagen type IV alpha 1 chain.	0.637
COL1A1	COL5A2	ENSCHIP00000023918	ENSCHIP00000009695	Collagen type I alpha 1 chain.	Collagen type V alpha 2 chain.	0.962