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ATP12A ATP12A COX6B1 COX6B1 NDUFB3 NDUFB3 NDUFV1 NDUFV1 OXA1L OXA1L ATP6V0D2 ATP6V0D2 NDUFA11 NDUFA11 ATP5PF ATP5PF ATP5MF ATP5MF NDUFB9 NDUFB9 NDUFS6 NDUFS6 COX6B2 COX6B2 ATP4A ATP4A NDUFB6 NDUFB6 COX1 COX1 COX2 COX2 COX3 COX3 NDUFA1 NDUFA1 SDHD SDHD ATP6V1E2 ATP6V1E2 PPA2 PPA2 NDUFS7 NDUFS7 LOC108638252 LOC108638252 SDHC SDHC NDUFA7 NDUFA7 BCS1L BCS1L ATP4B ATP4B LOC102191741 LOC102191741 ATP6V1G3 ATP6V1G3 ATP5MC2 ATP5MC2 ATP5F1B ATP5F1B NDUFA3 NDUFA3 NDUFAB1 NDUFAB1 ATP5PB ATP5PB NDUFS8 NDUFS8 SDHB SDHB ACTB ACTB NDUFB7 NDUFB7 ATP5ME ATP5ME NDUFA6 NDUFA6 NDUFB4 NDUFB4 ESR1 ESR1 ATP6V0A2 ATP6V0A2 NDUFB8 NDUFB8 COX7A2L COX7A2L NDUFA10 NDUFA10 ATP5F1A ATP5F1A NDUFA5 NDUFA5 NDUFA4 NDUFA4 NDUFS1 NDUFS1 UQCRC1 UQCRC1 UQCRFS1 UQCRFS1 NDUFV2 NDUFV2 NDUFC1 NDUFC1 PPA1 PPA1 NDUFS5 NDUFS5 COX5B COX5B UQCRC2 UQCRC2 ATP5MC1 ATP5MC1 LHPP LHPP ATP6V1C2 ATP6V1C2 UQCRQ UQCRQ NDUFS3 NDUFS3 NDUFB10 NDUFB10 SDHA SDHA ATP5MC3 ATP5MC3 ATP5F1C ATP5F1C COX6A2 COX6A2 NDUFA2 NDUFA2 BMP6 BMP6 LOC106501717 LOC106501717 ATP5PD ATP5PD NDUFV3 NDUFV3 LOC102173997 LOC102173997 BGLAP BGLAP NDUFS4 NDUFS4 NDUFB5 NDUFB5 NDUFC2 NDUFC2 NDUFS2 NDUFS2 COX8A COX8A NDUFA8 NDUFA8
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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ATP12ASodium/potassium-transporting ATPase subunit alpha. (1074 aa)
COX6B1Cytochrome c oxidase subunit 6B1. (99 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
OXA1LOXA1L mitochondrial inner membrane protein. (435 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
NDUFA11Uncharacterized protein. (141 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
ATP5MFUncharacterized protein. (104 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa)
COX6B2Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (128 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (70 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
PPA2Uncharacterized protein. (342 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (238 aa)
LOC108638252ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
SDHCSuccinate dehydrogenase complex subunit C. (169 aa)
NDUFA7Uncharacterized protein. (126 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC102191741Uncharacterized protein. (152 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ATP5MC2ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (143 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
NDUFA3Uncharacterized protein. (84 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
NDUFS8Uncharacterized protein. (212 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
ACTBUncharacterized protein. (375 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
ATP5MEUncharacterized protein. (71 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (108 aa)
NDUFA4NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex 4. (82 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (727 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
NDUFC1Uncharacterized protein. (76 aa)
PPA1Pyrophosphatase (inorganic) 1. (289 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
COX5BCytochrome c oxidase subunit 5B. (143 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
ATP5MC1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
LHPPPhospholysine phosphohistidine inorganic pyrophosphate phosphatase. (270 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
ATP5MC3ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
LOC106501717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (162 aa)
NDUFV3Uncharacterized protein. (109 aa)
LOC102173997Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (97 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (189 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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