STRINGSTRING
GLB1 GLB1 CDT1 CDT1 LOC102169981 LOC102169981 LOC102171353 LOC102171353 GINS1 GINS1 GINS3 GINS3 CD4 CD4 LOC108633916 LOC108633916 LOC106503499 LOC106503499 LOC102180554 LOC102180554 POLD2 POLD2 CDC6 CDC6 LOC108634231 LOC108634231 H3-4 H3-4 POLE POLE LOC108636012 LOC108636012 LOC102182848 LOC102182848 FLT3 FLT3 CD34 CD34 CD5 CD5 LOC108633554 LOC108633554 LOC102185882 LOC102185882 LOC102191748 LOC102191748 LOC102189503 LOC102189503 GLB1L3 GLB1L3 CD19 CD19 POLE4 POLE4 POLE2 POLE2 TP53 TP53 POLE3 POLE3 POLD1 POLD1 MCM4 MCM4 POLA1 POLA1 GSR GSR PCNA PCNA CDC45 CDC45
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLB1Beta-galactosidase. (646 aa)
CDT1Chromatin licensing and DNA replication factor 1. (637 aa)
LOC102169981Histone domain-containing protein. (136 aa)
LOC102171353Histone H3; Belongs to the histone H3 family. (136 aa)
GINS1GINS complex subunit 1. (196 aa)
GINS3GINS complex subunit 3. (216 aa)
CD4CD4 molecule. (455 aa)
LOC108633916Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106503499Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102180554Histone H3; Belongs to the histone H3 family. (136 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (562 aa)
LOC108634231Histone H3; Belongs to the histone H3 family. (136 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
LOC108636012Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102182848Histone H3; Belongs to the histone H3 family. (136 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (992 aa)
CD34Uncharacterized protein. (384 aa)
CD5CD5 molecule. (505 aa)
LOC108633554Histone domain-containing protein. (136 aa)
LOC102185882Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102191748Histone domain-containing protein. (136 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
GLB1L3Beta-galactosidase. (664 aa)
CD19CD19 molecule. (561 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (131 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
POLE3CBFD_NFYB_HMF domain-containing protein. (147 aa)
POLD1DNA polymerase. (1115 aa)
MCM4DNA helicase; Belongs to the MCM family. (851 aa)
POLA1DNA polymerase. (1468 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CDC45Cell division cycle 45. (524 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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