30 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OSM	Oncostatin M. (239 aa)
	GPT2	Glutamic--pyruvic transaminase 2. (523 aa)
	CYP1A1	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (520 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
	GOT1	Aspartate aminotransferase. (413 aa)
	CCL2	C-C motif chemokine. (98 aa)
	EPCAM	Epithelial cell adhesion molecule. (314 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	LOC102185401	SERPIN domain-containing protein; Belongs to the serpin family. (441 aa)
	CD44	CD44 molecule (Indian blood group). (715 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SOX17	SRY-box transcription factor 17. (410 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	ALB	Serum albumin. (608 aa)
	TAT	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (447 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (486 aa)
	GPT	Glutamic--pyruvic transaminase. (496 aa)
	PXDN	Peroxidasin. (1525 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	ACTB	Uncharacterized protein. (375 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	CYP1A2	Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (533 aa)
	NCAM1	Neural cell adhesion molecule 1. (1007 aa)
	FAH	Fumarylacetoacetase. (419 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	ENSCHIP00000007600	Uncharacterized protein. (352 aa)
	HGF	Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa)
	AFP	Alpha fetoprotein. (610 aa)
	PKLR	Pyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	AFP	ENSCHIP00000011080	ENSCHIP00000003990	Uncharacterized protein.	Alpha fetoprotein.	0.682
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	BMP4	ENSCHIP00000011080	ENSCHIP00000023678	Uncharacterized protein.	Bone morphogenetic protein 4.	0.697
ACTB	CAV1	ENSCHIP00000011080	ENSCHIP00000020742	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.830
ACTB	CCL2	ENSCHIP00000011080	ENSCHIP00000027804	Uncharacterized protein.	C-C motif chemokine.	0.764
ACTB	CD44	ENSCHIP00000011080	ENSCHIP00000024231	Uncharacterized protein.	CD44 molecule (Indian blood group).	0.835
ACTB	CYP1A1	ENSCHIP00000011080	ENSCHIP00000031186	Uncharacterized protein.	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	0.666
ACTB	CYP1A2	ENSCHIP00000011080	ENSCHIP00000010761	Uncharacterized protein.	Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.	0.472
ACTB	ENSCHIP00000007600	ENSCHIP00000011080	ENSCHIP00000007600	Uncharacterized protein.	Uncharacterized protein.	0.630
ACTB	EPCAM	ENSCHIP00000011080	ENSCHIP00000026828	Uncharacterized protein.	Epithelial cell adhesion molecule.	0.658
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	GOT1	ENSCHIP00000011080	ENSCHIP00000029101	Uncharacterized protein.	Aspartate aminotransferase.	0.779
ACTB	GOT2	ENSCHIP00000011080	ENSCHIP00000010968	Uncharacterized protein.	Aspartate aminotransferase.	0.779
ACTB	GPT	ENSCHIP00000011080	ENSCHIP00000016856	Uncharacterized protein.	Glutamic--pyruvic transaminase.	0.642
ACTB	GPT2	ENSCHIP00000011080	ENSCHIP00000033599	Uncharacterized protein.	Glutamic--pyruvic transaminase 2.	0.613
ACTB	HGF	ENSCHIP00000011080	ENSCHIP00000005606	Uncharacterized protein.	Hepatocyte growth factor; Belongs to the peptidase S1 family.	0.717
ACTB	INS	ENSCHIP00000011080	ENSCHIP00000007610	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.884
ACTB	LOC102185401	ENSCHIP00000011080	ENSCHIP00000024460	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.482
ACTB	PKM	ENSCHIP00000011080	ENSCHIP00000015417	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.744
ACTB	PXDN	ENSCHIP00000011080	ENSCHIP00000015493	Uncharacterized protein.	Peroxidasin.	0.962