STRINGSTRING
LOC102172226 LOC102172226 H2BC12 H2BC12 PGK2 PGK2 FANCA FANCA LOC102181912 LOC102181912 LOC102175243 LOC102175243 H2BC18 H2BC18 TERT TERT LOC102179187 LOC102179187 H2BC1 H2BC1 KDM1A KDM1A H2BC15 H2BC15 H2BU1 H2BU1 H2BC5 H2BC5 PGK1 PGK1 SMARCA1 SMARCA1 H2BC3 H2BC3 H2BC11 H2BC11 H2BE1 H2BE1 H2BC21 H2BC21 ACTB ACTB FANCM FANCM PCNA PCNA PXDN PXDN PSPC1 PSPC1 PSIP1 PSIP1 THOC2 THOC2 KIF4A KIF4A BRCA2 BRCA2 GNL3 GNL3 MUS81 MUS81 HLTF HLTF SMARCAL1 SMARCAL1 ZRANB3 ZRANB3 FANCD2 FANCD2 BRCA1 BRCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102172226Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
H2BC12Histone H2B; Belongs to the histone H2B family. (126 aa)
PGK2Phosphoglycerate kinase. (417 aa)
FANCAFA complementation group A. (1416 aa)
LOC102181912Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102175243Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
LOC102179187Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (873 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
PGK1Phosphoglycerate kinase. (424 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1114 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
ACTBUncharacterized protein. (375 aa)
FANCMFA complementation group M. (2043 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PXDNPeroxidasin. (1525 aa)
PSPC1Paraspeckle component 1. (520 aa)
PSIP1PWWP domain-containing protein. (530 aa)
THOC2Uncharacterized protein. (1591 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1232 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
GNL3G protein nucleolar 3. (544 aa)
MUS81MUS81 structure-specific endonuclease subunit. (552 aa)
HLTFHelicase like transcription factor. (1011 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
ZRANB3Zinc finger RANBP2-type containing 3. (1070 aa)
FANCD2FA complementation group D2. (1423 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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