(8 nodes) (2018) MiR-1260b inhibitor enhances the chemosensitivity of colorectal cancer cells to fluorouracil by targeting PDCD4IGF1. network (Capra hircus)

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Your Input:
	SMAD4	Mothers against decapentaplegic homolog. (513 aa)
	PLAT	Plasminogen activator; Belongs to the peptidase S1 family. (565 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1607 aa)
	MYB	MYB proto-oncogene, transcription factor. (640 aa)
	ACTB	Uncharacterized protein. (375 aa)
	EIF4G2	Eukaryotic translation initiation factor 4 gamma 2. (905 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
	EIF4G3	Eukaryotic translation initiation factor 4 gamma 3. (1584 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	IGF1	ENSCHIP00000011080	ENSCHIP00000020185	Uncharacterized protein.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.790
ACTB	PLAT	ENSCHIP00000011080	ENSCHIP00000000197	Uncharacterized protein.	Plasminogen activator; Belongs to the peptidase S1 family.	0.684
ACTB	SMAD4	ENSCHIP00000011080	ENSCHIP00000020573	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.774
EIF4G1	EIF4G2	ENSCHIP00000005945	ENSCHIP00000018662	Eukaryotic translation initiation factor 4 gamma 1.	Eukaryotic translation initiation factor 4 gamma 2.	0.955
EIF4G1	EIF4G3	ENSCHIP00000005945	ENSCHIP00000020204	Eukaryotic translation initiation factor 4 gamma 1.	Eukaryotic translation initiation factor 4 gamma 3.	0.929
EIF4G2	EIF4G1	ENSCHIP00000018662	ENSCHIP00000005945	Eukaryotic translation initiation factor 4 gamma 2.	Eukaryotic translation initiation factor 4 gamma 1.	0.955
EIF4G2	EIF4G3	ENSCHIP00000018662	ENSCHIP00000020204	Eukaryotic translation initiation factor 4 gamma 2.	Eukaryotic translation initiation factor 4 gamma 3.	0.944
EIF4G3	EIF4G1	ENSCHIP00000020204	ENSCHIP00000005945	Eukaryotic translation initiation factor 4 gamma 3.	Eukaryotic translation initiation factor 4 gamma 1.	0.929
EIF4G3	EIF4G2	ENSCHIP00000020204	ENSCHIP00000018662	Eukaryotic translation initiation factor 4 gamma 3.	Eukaryotic translation initiation factor 4 gamma 2.	0.944
IGF1	ACTB	ENSCHIP00000020185	ENSCHIP00000011080	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Uncharacterized protein.	0.790
PLAT	ACTB	ENSCHIP00000000197	ENSCHIP00000011080	Plasminogen activator; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.684
SMAD4	ACTB	ENSCHIP00000020573	ENSCHIP00000011080	Mothers against decapentaplegic homolog.	Uncharacterized protein.	0.774