STRINGSTRING
SAV1 SAV1 LRIG1 LRIG1 OLFM4 OLFM4 TGFB1 TGFB1 TGFBR2 TGFBR2 ATOH1 ATOH1 ASCL2 ASCL2 EREG EREG BMPR1A BMPR1A LATS1 LATS1 CTNNB1 CTNNB1 PLP1 PLP1 MOB1A MOB1A TGFB2 TGFB2 GLB1L3 GLB1L3 CD44 CD44 NOG NOG BMP4 BMP4 EGFR EGFR AXIN2 AXIN2 SMAD2 SMAD2 WNT3 WNT3 ACVR1B ACVR1B LGR5 LGR5 LTBP4 LTBP4 PLP2 PLP2 PXDN PXDN AREG AREG JAG2 JAG2 CHGA CHGA DLL4 DLL4 GLB1 GLB1 SMAD3 SMAD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SAV1Salvador family WW domain containing protein 1. (384 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)
OLFM4Olfactomedin 4. (543 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
ATOH1Atonal bHLH transcription factor 1. (352 aa)
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)
EREGEpiregulin. (163 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LATS1Large tumor suppressor kinase 1. (1145 aa)
CTNNB1Catenin beta 1. (781 aa)
PLP1Proteolipid protein 1. (277 aa)
MOB1AMOB kinase activator 1A. (219 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GLB1L3Beta-galactosidase. (664 aa)
CD44CD44 molecule (Indian blood group). (715 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
AXIN2Axin 2. (844 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1625 aa)
PLP2MARVEL domain-containing protein. (152 aa)
PXDNPeroxidasin. (1525 aa)
AREGAmphiregulin. (264 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1069 aa)
CHGAChromogranin A. (534 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
GLB1Beta-galactosidase. (646 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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