(33 nodes) (2019) ZRANB2SNHG20FOXK1 Axis regulates Vasculogenic mimicry formation in glioma. network (Capra hircus)

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Your Input:
	MMUT	Methylmalonyl-CoA mutase. (771 aa)
	STAU1	Uncharacterized protein. (577 aa)
	CD34	Uncharacterized protein. (384 aa)
	CDK2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
	ADAM10	ADAM metallopeptidase domain 10. (750 aa)
	PCBP1	Poly(rC) binding protein 1. (356 aa)
	ZRANB2	Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family. (330 aa)
	AGO2	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa)
	SRSF1	Uncharacterized protein. (248 aa)
	HMGA1	High mobility group AT-hook 1. (105 aa)
	UPF1	UPF1 RNA helicase and ATPase. (1126 aa)
	LIN28B	Lin-28 homolog B. (255 aa)
	CDK6	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (452 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (275 aa)
	CCNA1	Cyclin A1; Belongs to the cyclin family. (421 aa)
	ELAVL1	ELAV-like protein; Belongs to the RRM elav family. (326 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	KRT80	Keratin 80; Belongs to the intermediate filament family. (451 aa)
	PXDN	Peroxidasin. (1525 aa)
	BCL2	BH4_2 domain-containing protein. (229 aa)
	MMP9	Uncharacterized protein. (709 aa)
	GAP43	Growth associated protein 43. (238 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	EGFR	Receptor protein-tyrosine kinase. (1208 aa)
	FOXK1	Forkhead box K1. (708 aa)
	FOXK2	Forkhead box K2. (658 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	PAX3	Paired box 3. (484 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CDKN2B	Cyclin dependent kinase inhibitor 2B. (138 aa)
	CDKN2A	Cyclin dependent kinase inhibitor 2A. (157 aa)
	LIG1	DNA ligase. (915 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	BCL2	ENSCHIP00000003360	ENSCHIP00000015831	ADAM metallopeptidase domain 10.	BH4_2 domain-containing protein.	0.479
ADAM10	EGFR	ENSCHIP00000003360	ENSCHIP00000022759	ADAM metallopeptidase domain 10.	Receptor protein-tyrosine kinase.	0.562
ADAM10	GAPDH	ENSCHIP00000003360	ENSCHIP00000025974	ADAM metallopeptidase domain 10.	Glyceraldehyde-3-phosphate dehydrogenase.	0.655
ADAM10	MMP9	ENSCHIP00000003360	ENSCHIP00000016938	ADAM metallopeptidase domain 10.	Uncharacterized protein.	0.685
ADAM10	PXDN	ENSCHIP00000003360	ENSCHIP00000015493	ADAM metallopeptidase domain 10.	Peroxidasin.	0.565
AGO2	BCL2	ENSCHIP00000006557	ENSCHIP00000015831	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	BH4_2 domain-containing protein.	0.574
AGO2	CASP3	ENSCHIP00000006557	ENSCHIP00000011490	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Caspase 3; Belongs to the peptidase C14A family.	0.538
AGO2	CDK6	ENSCHIP00000006557	ENSCHIP00000008415	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	0.451
AGO2	CTNNB1	ENSCHIP00000006557	ENSCHIP00000031016	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Catenin beta 1.	0.568
AGO2	EGFR	ENSCHIP00000006557	ENSCHIP00000022759	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Receptor protein-tyrosine kinase.	0.591
AGO2	ELAVL1	ENSCHIP00000006557	ENSCHIP00000012648	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	ELAV-like protein; Belongs to the RRM elav family.	0.667
AGO2	GAPDH	ENSCHIP00000006557	ENSCHIP00000025974	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Glyceraldehyde-3-phosphate dehydrogenase.	0.824
AGO2	LIN28B	ENSCHIP00000006557	ENSCHIP00000007713	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Lin-28 homolog B.	0.419
AGO2	MMP9	ENSCHIP00000006557	ENSCHIP00000016938	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Uncharacterized protein.	0.409
AGO2	MMUT	ENSCHIP00000006557	ENSCHIP00000027222	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Methylmalonyl-CoA mutase.	0.905
AGO2	PXDN	ENSCHIP00000006557	ENSCHIP00000015493	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Peroxidasin.	0.637
AGO2	STAU1	ENSCHIP00000006557	ENSCHIP00000001101	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Uncharacterized protein.	0.676
AGO2	UPF1	ENSCHIP00000006557	ENSCHIP00000007632	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	UPF1 RNA helicase and ATPase.	0.761
AKT2	BCL2	ENSCHIP00000013931	ENSCHIP00000015831	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BH4_2 domain-containing protein.	0.957
AKT2	CASP3	ENSCHIP00000013931	ENSCHIP00000011490	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase 3; Belongs to the peptidase C14A family.	0.687