38 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108636012	Histone H3; Belongs to the histone H3 family. (136 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (330 aa)
	LOC102191748	Histone domain-containing protein. (136 aa)
	LOC102185882	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108633554	Histone domain-containing protein. (136 aa)
	LOC102182848	Histone H3; Belongs to the histone H3 family. (136 aa)
	H3-4	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108634231	Histone H3; Belongs to the histone H3 family. (136 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	LOC102180554	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC106503499	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108633916	Histone H3; Belongs to the histone H3 family. (136 aa)
	SIRT1	Deacetylase sirtuin-type domain-containing protein. (732 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	LOC102171353	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC102169981	Histone domain-containing protein. (136 aa)
	ACADL	Acyl-CoA dehydrogenase long chain. (430 aa)
	ACADS	Acyl-CoA dehydrogenase short chain. (412 aa)
	LOC102190925	Uncharacterized protein. (419 aa)
	PDK4	Protein-serine/threonine kinase. (407 aa)
	FABP3	Heart-type fatty acid binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	PXDN	Peroxidasin. (1525 aa)
	ALB	Serum albumin. (608 aa)
	SLC2A4	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	LOC102189503	Histone H3; Belongs to the histone H3 family. (136 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (719 aa)
	HADHA	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	ACADSB	Acyl-CoA dehydrogenase short/branched chain. (434 aa)
	HADHB	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
	CD36	Uncharacterized protein; Belongs to the CD36 family. (472 aa)
	ACADVL	Acyl-CoA dehydrogenase very long chain. (655 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (470 aa)
	SLC27A1	Solute carrier family 27 member 1. (646 aa)
	GSK3A	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADL	ACADVL	ENSCHIP00000009763	ENSCHIP00000030708	Acyl-CoA dehydrogenase long chain.	Acyl-CoA dehydrogenase very long chain.	0.950
ACADL	ACSL1	ENSCHIP00000009763	ENSCHIP00000026081	Acyl-CoA dehydrogenase long chain.	Acyl-CoA synthetase long chain family member 1.	0.773
ACADL	CD36	ENSCHIP00000009763	ENSCHIP00000030240	Acyl-CoA dehydrogenase long chain.	Uncharacterized protein; Belongs to the CD36 family.	0.630
ACADL	ECHS1	ENSCHIP00000009763	ENSCHIP00000000678	Acyl-CoA dehydrogenase long chain.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.737
ACADL	FABP3	ENSCHIP00000009763	ENSCHIP00000012241	Acyl-CoA dehydrogenase long chain.	Heart-type fatty acid binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.492
ACADL	FABP4	ENSCHIP00000009763	ENSCHIP00000004118	Acyl-CoA dehydrogenase long chain.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.548
ACADL	HADHA	ENSCHIP00000009763	ENSCHIP00000026358	Acyl-CoA dehydrogenase long chain.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.	0.986
ACADL	HADHB	ENSCHIP00000009763	ENSCHIP00000029745	Acyl-CoA dehydrogenase long chain.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
ACADL	LOC102190925	ENSCHIP00000009763	ENSCHIP00000010386	Acyl-CoA dehydrogenase long chain.	Uncharacterized protein.	0.966
ACADL	PDK4	ENSCHIP00000009763	ENSCHIP00000011231	Acyl-CoA dehydrogenase long chain.	Protein-serine/threonine kinase.	0.673
ACADL	PPARA	ENSCHIP00000009763	ENSCHIP00000032439	Acyl-CoA dehydrogenase long chain.	Peroxisome proliferator activated receptor alpha.	0.667
ACADL	PPARG	ENSCHIP00000009763	ENSCHIP00000015163	Acyl-CoA dehydrogenase long chain.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.576
ACADL	SIRT1	ENSCHIP00000009763	ENSCHIP00000007571	Acyl-CoA dehydrogenase long chain.	Deacetylase sirtuin-type domain-containing protein.	0.403
ACADL	SLC27A1	ENSCHIP00000009763	ENSCHIP00000033688	Acyl-CoA dehydrogenase long chain.	Solute carrier family 27 member 1.	0.627
ACADL	SLC2A4	ENSCHIP00000009763	ENSCHIP00000022482	Acyl-CoA dehydrogenase long chain.	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.457
ACADS	ACADSB	ENSCHIP00000010131	ENSCHIP00000029528	Acyl-CoA dehydrogenase short chain.	Acyl-CoA dehydrogenase short/branched chain.	0.947
ACADS	ACADVL	ENSCHIP00000010131	ENSCHIP00000030708	Acyl-CoA dehydrogenase short chain.	Acyl-CoA dehydrogenase very long chain.	0.439
ACADS	ACSL1	ENSCHIP00000010131	ENSCHIP00000026081	Acyl-CoA dehydrogenase short chain.	Acyl-CoA synthetase long chain family member 1.	0.661
ACADS	ECHS1	ENSCHIP00000010131	ENSCHIP00000000678	Acyl-CoA dehydrogenase short chain.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.954
ACADS	FABP3	ENSCHIP00000010131	ENSCHIP00000012241	Acyl-CoA dehydrogenase short chain.	Heart-type fatty acid binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.586