STRINGSTRING
PITX1 PITX1 HOXB6 HOXB6 HOXB2 HOXB2 HOXB4 HOXB4 HOXC11 HOXC11 SIM2 SIM2 RPS9 RPS9 ZIC2 ZIC2 CAPN3 CAPN3 ZIC4 ZIC4 HOXB5 HOXB5 PAX3 PAX3 HOXB9 HOXB9 IGFN1 IGFN1 MYOG MYOG TBX4 TBX4 HOXA11 HOXA11 SLC2A4 SLC2A4 MYL2 MYL2 LEP LEP IGF1 IGF1 HOXB7 HOXB7 MYL1 MYL1 MYF5 MYF5 C1S C1S PITX2 PITX2 ACTN2 ACTN2 HOXC8 HOXC8 MYOD1 MYOD1 FOXD1 FOXD1 PITX3 PITX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PITX1Homeobox protein. (314 aa)
HOXB6Homeobox B6. (224 aa)
HOXB2Homeobox B2. (354 aa)
HOXB4Homeobox B4. (251 aa)
HOXC11Homeobox C11. (304 aa)
SIM2SIM bHLH transcription factor 2. (672 aa)
RPS9Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
ZIC2Zic family member 2. (528 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (819 aa)
ZIC4Zic family member 4. (335 aa)
HOXB5Homeobox B5. (269 aa)
PAX3Paired box 3. (484 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
IGFN1Uncharacterized protein. (1295 aa)
MYOGMyogenin. (224 aa)
TBX4T-box transcription factor 4. (556 aa)
HOXA11Homeobox A11. (317 aa)
SLC2A4MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
MYL2Myosin light chain 2. (178 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
HOXB7Homeobox B7. (217 aa)
MYL1Myosin light chain 1. (174 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (260 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (701 aa)
PITX2Homeobox protein. (325 aa)
ACTN2Actinin alpha 2. (902 aa)
HOXC8Homeobox C8. (242 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
FOXD1Forkhead box D1. (479 aa)
PITX3Homeobox protein. (302 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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