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PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (401 aa) | ||||
PRIM2 | Uncharacterized protein. (219 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
CYP2E1 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (495 aa) |