STRINGSTRING
CSF2 CSF2 CSF1R CSF1R SLC27A4 SLC27A4 CD36 CD36 PTGES PTGES PTGS2 PTGS2 HADHA HADHA GAPDH GAPDH KIT KIT AASDH AASDH RET RET IFNG IFNG PXDN PXDN CPT1A CPT1A LOC102190925 LOC102190925 CD4 CD4 CTLA4 CTLA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF2Granulocyte-macrophage colony stimulating factor. (144 aa)
CSF1RColony stimulating factor 1 receptor. (958 aa)
SLC27A4Solute carrier family 27 member 4. (643 aa)
CD36Uncharacterized protein; Belongs to the CD36 family. (472 aa)
PTGESProstaglandin E synthase. (153 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1106 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
PXDNPeroxidasin. (1525 aa)
CPT1ACarnitine O-palmitoyltransferase 1; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
LOC102190925Uncharacterized protein. (419 aa)
CD4CD4 molecule. (455 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (221 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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