30 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD34	Uncharacterized protein. (384 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	MX1	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (654 aa)
	VCL	Vinculin. (1134 aa)
	CCND3	Cyclin D3; Belongs to the cyclin family. (292 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
	RPL22	Ribosomal protein L22. (128 aa)
	NKX2-1	NK2 homeobox 1. (370 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	NOTCH1	Notch receptor 1. (2508 aa)
	CDK4	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
	PBX3	PBX homeobox 3. (434 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	BCL2	BH4_2 domain-containing protein. (229 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	RPL5	Ribosomal_L18_c domain-containing protein. (296 aa)
	GATA2	GATA binding protein 2. (480 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	ACTB	Uncharacterized protein. (375 aa)
	JAK1	Tyrosine-protein kinase. (1159 aa)
	LOC102179869	Ribosomal_L18_c domain-containing protein. (297 aa)
	PSPH	Phosphoserine phosphatase. (225 aa)
	IKZF2	IKAROS family zinc finger 2. (526 aa)
	HOXA13	Homeobox A13. (388 aa)
	CDK2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
	PKLR	Pyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	BCL2	ENSCHIP00000011080	ENSCHIP00000015831	Uncharacterized protein.	BH4_2 domain-containing protein.	0.940
ACTB	CCND3	ENSCHIP00000011080	ENSCHIP00000033357	Uncharacterized protein.	Cyclin D3; Belongs to the cyclin family.	0.681
ACTB	CD34	ENSCHIP00000011080	ENSCHIP00000002645	Uncharacterized protein.	Uncharacterized protein.	0.812
ACTB	CDK2	ENSCHIP00000011080	ENSCHIP00000003142	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.838
ACTB	CDK4	ENSCHIP00000011080	ENSCHIP00000022710	Uncharacterized protein.	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	0.824
ACTB	FOS	ENSCHIP00000011080	ENSCHIP00000030757	Uncharacterized protein.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.619
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	JAK1	ENSCHIP00000011080	ENSCHIP00000010087	Uncharacterized protein.	Tyrosine-protein kinase.	0.746
ACTB	JUN	ENSCHIP00000011080	ENSCHIP00000001903	Uncharacterized protein.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.681
ACTB	MX1	ENSCHIP00000011080	ENSCHIP00000001236	Uncharacterized protein.	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.720
ACTB	NOTCH1	ENSCHIP00000011080	ENSCHIP00000023681	Uncharacterized protein.	Notch receptor 1.	0.775
ACTB	PFKP	ENSCHIP00000011080	ENSCHIP00000030216	Uncharacterized protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.663
ACTB	PKM	ENSCHIP00000011080	ENSCHIP00000015417	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.744
ACTB	VCL	ENSCHIP00000011080	ENSCHIP00000000453	Uncharacterized protein.	Vinculin.	0.988
BCL2	ACTB	ENSCHIP00000015831	ENSCHIP00000011080	BH4_2 domain-containing protein.	Uncharacterized protein.	0.940
BCL2	CCND3	ENSCHIP00000015831	ENSCHIP00000033357	BH4_2 domain-containing protein.	Cyclin D3; Belongs to the cyclin family.	0.608
BCL2	CD34	ENSCHIP00000015831	ENSCHIP00000002645	BH4_2 domain-containing protein.	Uncharacterized protein.	0.718
BCL2	CDK2	ENSCHIP00000015831	ENSCHIP00000003142	BH4_2 domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.820
BCL2	CDK4	ENSCHIP00000015831	ENSCHIP00000022710	BH4_2 domain-containing protein.	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	0.825
BCL2	FOS	ENSCHIP00000015831	ENSCHIP00000030757	BH4_2 domain-containing protein.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.640