34 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IARS1	Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1262 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
	ODC1	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
	ANXA4	Annexin. (320 aa)
	ANXA2	Annexin. (339 aa)
	LOC102173140	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (440 aa)
	EIF4E	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
	ANXA3	Annexin. (323 aa)
	ANXA13	Annexin. (371 aa)
	ENSCHIP00000009938	Annexin. (100 aa)
	TBC1D16	TBC1 domain family member 16. (763 aa)
	ACTB	Uncharacterized protein. (375 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (275 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	ATF4	Activating transcription factor 4. (352 aa)
	ATF3	Activating transcription factor 3. (181 aa)
	PXDN	Peroxidasin. (1525 aa)
	ANXA6	Annexin. (689 aa)
	NARS1	Asparaginyl-tRNA synthetase. (559 aa)
	SLC43A1	Solute carrier family 43 member 1. (570 aa)
	LOC102182731	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (453 aa)
	ENSCHIP00000022284	Annexin. (275 aa)
	ANXA1	Annexin. (346 aa)
	SLC1A5	Amino acid transporter. (530 aa)
	MTHFD2	Uncharacterized protein. (352 aa)
	ANXA5	Annexin. (334 aa)
	PAX3	Paired box 3. (484 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	LOC108634039	Annexin. (449 aa)
	ANXA9	Annexin. (345 aa)
	LOC102176495	Annexin. (331 aa)
	ANXA11	Annexin. (503 aa)
	ANXA7	Annexin. (485 aa)
	SLC38A1	Solute carrier family 38 member 1. (486 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ANXA1	ENSCHIP00000011080	ENSCHIP00000023293	Uncharacterized protein.	Annexin.	0.799
ACTB	ANXA11	ENSCHIP00000011080	ENSCHIP00000000173	Uncharacterized protein.	Annexin.	0.767
ACTB	ANXA13	ENSCHIP00000011080	ENSCHIP00000009473	Uncharacterized protein.	Annexin.	0.768
ACTB	ANXA2	ENSCHIP00000011080	ENSCHIP00000002620	Uncharacterized protein.	Annexin.	0.870
ACTB	ANXA3	ENSCHIP00000011080	ENSCHIP00000008438	Uncharacterized protein.	Annexin.	0.768
ACTB	ANXA4	ENSCHIP00000011080	ENSCHIP00000033451	Uncharacterized protein.	Annexin.	0.769
ACTB	ANXA5	ENSCHIP00000011080	ENSCHIP00000024678	Uncharacterized protein.	Annexin.	0.867
ACTB	ANXA6	ENSCHIP00000011080	ENSCHIP00000016041	Uncharacterized protein.	Annexin.	0.768
ACTB	ANXA7	ENSCHIP00000011080	ENSCHIP00000000188	Uncharacterized protein.	Annexin.	0.767
ACTB	ANXA9	ENSCHIP00000011080	ENSCHIP00000028656	Uncharacterized protein.	Annexin.	0.768
ACTB	ATF3	ENSCHIP00000011080	ENSCHIP00000014267	Uncharacterized protein.	Activating transcription factor 3.	0.608
ACTB	ATF4	ENSCHIP00000011080	ENSCHIP00000013483	Uncharacterized protein.	Activating transcription factor 4.	0.683
ACTB	CASP3	ENSCHIP00000011080	ENSCHIP00000011490	Uncharacterized protein.	Caspase 3; Belongs to the peptidase C14A family.	0.996
ACTB	EIF4E	ENSCHIP00000011080	ENSCHIP00000005408	Uncharacterized protein.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.712
ACTB	ENSCHIP00000009938	ENSCHIP00000011080	ENSCHIP00000009938	Uncharacterized protein.	Annexin.	0.767
ACTB	ENSCHIP00000022284	ENSCHIP00000011080	ENSCHIP00000022284	Uncharacterized protein.	Annexin.	0.806
ACTB	LOC102176495	ENSCHIP00000011080	ENSCHIP00000000108	Uncharacterized protein.	Annexin.	0.769
ACTB	LOC108634039	ENSCHIP00000011080	ENSCHIP00000027686	Uncharacterized protein.	Annexin.	0.767
ACTB	ODC1	ENSCHIP00000011080	ENSCHIP00000033430	Uncharacterized protein.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.406
ACTB	PAX3	ENSCHIP00000011080	ENSCHIP00000026819	Uncharacterized protein.	Paired box 3.	0.464