9 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MTHFD1	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
	SLC25A32	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ACTB	Uncharacterized protein. (375 aa)
	MTHFD2	Uncharacterized protein. (352 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	LCK	ENSCHIP00000011080	ENSCHIP00000011857	Uncharacterized protein.	Tyrosine-protein kinase.	0.650
ACTB	MYC	ENSCHIP00000011080	ENSCHIP00000011576	Uncharacterized protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.716
GAPDH	ACTB	ENSCHIP00000025974	ENSCHIP00000011080	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.979
GAPDH	LCK	ENSCHIP00000025974	ENSCHIP00000011857	Glyceraldehyde-3-phosphate dehydrogenase.	Tyrosine-protein kinase.	0.526
GAPDH	MYC	ENSCHIP00000025974	ENSCHIP00000011576	Glyceraldehyde-3-phosphate dehydrogenase.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.739
GAPDH	SHMT1	ENSCHIP00000025974	ENSCHIP00000011211	Glyceraldehyde-3-phosphate dehydrogenase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.436
GAPDH	SHMT2	ENSCHIP00000025974	ENSCHIP00000001693	Glyceraldehyde-3-phosphate dehydrogenase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.482
LCK	ACTB	ENSCHIP00000011857	ENSCHIP00000011080	Tyrosine-protein kinase.	Uncharacterized protein.	0.650
LCK	GAPDH	ENSCHIP00000011857	ENSCHIP00000025974	Tyrosine-protein kinase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.526
MTHFD1	MTHFD2	ENSCHIP00000001307	ENSCHIP00000024076	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	Uncharacterized protein.	0.979
MTHFD1	SHMT1	ENSCHIP00000001307	ENSCHIP00000011211	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.994
MTHFD1	SHMT2	ENSCHIP00000001307	ENSCHIP00000001693	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.993
MTHFD1	SLC25A32	ENSCHIP00000001307	ENSCHIP00000014343	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.615
MTHFD2	MTHFD1	ENSCHIP00000024076	ENSCHIP00000001307	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.979
MTHFD2	SHMT1	ENSCHIP00000024076	ENSCHIP00000011211	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.996
MTHFD2	SHMT2	ENSCHIP00000024076	ENSCHIP00000001693	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.997
MTHFD2	SLC25A32	ENSCHIP00000024076	ENSCHIP00000014343	Uncharacterized protein.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.480
MYC	ACTB	ENSCHIP00000011576	ENSCHIP00000011080	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Uncharacterized protein.	0.716
MYC	GAPDH	ENSCHIP00000011576	ENSCHIP00000025974	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Glyceraldehyde-3-phosphate dehydrogenase.	0.739