42 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PINK1	PTEN induced kinase 1. (587 aa)
	ND2	NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa)
	SDHD	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	LONP1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (963 aa)
	ERO1A	Endoplasmic reticulum oxidoreductase 1 alpha. (460 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (836 aa)
	LOC102191741	Uncharacterized protein. (152 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ACTB	Uncharacterized protein. (375 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	ATG13	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (517 aa)
	BAK1	BCL2 antagonist/killer 1. (211 aa)
	MFN2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	COX5B	Cytochrome c oxidase subunit 5B. (143 aa)
	BNIP3	BCL2 interacting protein 3. (193 aa)
	ATF5	Activating transcription factor 5. (287 aa)
	CHAC1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (260 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	FASN	Fatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. (2755 aa)
	NDUFA12	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
	ATF6	Activating transcription factor 6. (664 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (539 aa)
	SFTPC	Surfactant protein C. (190 aa)
	ALB	Serum albumin. (608 aa)
	HSPA9	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
	NDUFS6	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa)
	TRIB3	Tribbles pseudokinase 3. (357 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (747 aa)
	EPCAM	Epithelial cell adhesion molecule. (314 aa)
	CLPP	ATP-dependent Clp protease proteolytic subunit. (272 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	CALR	Calreticulin. (417 aa)
	XBP1	BZIP domain-containing protein. (261 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
	BCL2L1	BH4_2 domain-containing protein. (233 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
	HSPA5	Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family. (655 aa)
	PNPT1	Polyribonucleotide nucleotidyltransferase 1. (761 aa)
	SFTPB	Surfactant protein B. (374 aa)
	MCL1	MCL1 apoptosis regulator, BCL2 family member. (350 aa)
	NDUFB6	NADH:ubiquinone oxidoreductase subunit B6. (128 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	ATF6	ENSCHIP00000011080	ENSCHIP00000019493	Uncharacterized protein.	Activating transcription factor 6.	0.774
ACTB	ATG13	ENSCHIP00000011080	ENSCHIP00000013146	Uncharacterized protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.502
ACTB	BAK1	ENSCHIP00000011080	ENSCHIP00000015729	Uncharacterized protein.	BCL2 antagonist/killer 1.	0.409
ACTB	BNIP3	ENSCHIP00000011080	ENSCHIP00000016664	Uncharacterized protein.	BCL2 interacting protein 3.	0.659
ACTB	CALR	ENSCHIP00000011080	ENSCHIP00000027670	Uncharacterized protein.	Calreticulin.	0.735
ACTB	EPCAM	ENSCHIP00000011080	ENSCHIP00000026828	Uncharacterized protein.	Epithelial cell adhesion molecule.	0.658
ACTB	FASN	ENSCHIP00000011080	ENSCHIP00000019407	Uncharacterized protein.	Fatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.	0.723
ACTB	HSP90B1	ENSCHIP00000011080	ENSCHIP00000005878	Uncharacterized protein.	Heat shock protein 90 beta family member 1.	0.629
ACTB	HSPA5	ENSCHIP00000011080	ENSCHIP00000030268	Uncharacterized protein.	Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family.	0.713
ACTB	HSPA9	ENSCHIP00000011080	ENSCHIP00000021641	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.610
ACTB	MCL1	ENSCHIP00000011080	ENSCHIP00000033441	Uncharacterized protein.	MCL1 apoptosis regulator, BCL2 family member.	0.783
ACTB	MFN1	ENSCHIP00000011080	ENSCHIP00000024001	Uncharacterized protein.	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.637
ACTB	MFN2	ENSCHIP00000011080	ENSCHIP00000015994	Uncharacterized protein.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.786
ACTB	PINK1	ENSCHIP00000011080	ENSCHIP00000031148	Uncharacterized protein.	PTEN induced kinase 1.	0.718
ACTB	SFTPC	ENSCHIP00000011080	ENSCHIP00000019719	Uncharacterized protein.	Surfactant protein C.	0.540
ACTB	TGFB1	ENSCHIP00000011080	ENSCHIP00000008885	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.831
ACTB	TRIB3	ENSCHIP00000011080	ENSCHIP00000022310	Uncharacterized protein.	Tribbles pseudokinase 3.	0.408
ACTB	XBP1	ENSCHIP00000011080	ENSCHIP00000027960	Uncharacterized protein.	BZIP domain-containing protein.	0.770
ALB	ACTB	ENSCHIP00000020234	ENSCHIP00000011080	Serum albumin.	Uncharacterized protein.	0.961