(11 nodes) (2020) DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools. network (Capra hircus)

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Your Input:
	DCTPP1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (169 aa)
	UNG	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (311 aa)
	DCTD	Deoxycytidylate deaminase. (178 aa)
	HPRT1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	TK1	Thymidine kinase. (238 aa)
	PRTFDC1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	DCK	Deoxycytidine kinase. (260 aa)
	CTPS1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
	SAMHD1	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (606 aa)
	CDA	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDA	CTPS1	ENSCHIP00000033674	ENSCHIP00000032816	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.536
CDA	DCK	ENSCHIP00000033674	ENSCHIP00000030481	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Deoxycytidine kinase.	0.992
CDA	DCTD	ENSCHIP00000033674	ENSCHIP00000007073	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Deoxycytidylate deaminase.	0.723
CDA	DCTPP1	ENSCHIP00000033674	ENSCHIP00000004507	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.430
CDA	GAPDH	ENSCHIP00000033674	ENSCHIP00000025974	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.423
CDA	SAMHD1	ENSCHIP00000033674	ENSCHIP00000033520	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.	0.530
CDA	TK1	ENSCHIP00000033674	ENSCHIP00000016762	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Thymidine kinase.	0.988
CDA	UNG	ENSCHIP00000033674	ENSCHIP00000004039	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.	0.783
CTPS1	CDA	ENSCHIP00000032816	ENSCHIP00000033674	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.536
CTPS1	DCK	ENSCHIP00000032816	ENSCHIP00000030481	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Deoxycytidine kinase.	0.523
CTPS1	DCTD	ENSCHIP00000032816	ENSCHIP00000007073	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Deoxycytidylate deaminase.	0.401
CTPS1	DCTPP1	ENSCHIP00000032816	ENSCHIP00000004507	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.587
CTPS1	TK1	ENSCHIP00000032816	ENSCHIP00000016762	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Thymidine kinase.	0.647
DCK	CDA	ENSCHIP00000030481	ENSCHIP00000033674	Deoxycytidine kinase.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.992
DCK	CTPS1	ENSCHIP00000030481	ENSCHIP00000032816	Deoxycytidine kinase.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.523
DCK	DCTD	ENSCHIP00000030481	ENSCHIP00000007073	Deoxycytidine kinase.	Deoxycytidylate deaminase.	0.980
DCK	DCTPP1	ENSCHIP00000030481	ENSCHIP00000004507	Deoxycytidine kinase.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.948
DCK	SAMHD1	ENSCHIP00000030481	ENSCHIP00000033520	Deoxycytidine kinase.	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.	0.554
DCK	TK1	ENSCHIP00000030481	ENSCHIP00000016762	Deoxycytidine kinase.	Thymidine kinase.	0.788
DCTD	CDA	ENSCHIP00000007073	ENSCHIP00000033674	Deoxycytidylate deaminase.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.723