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FGA FGA XYLT2 XYLT2 SDC1 SDC1 ALB ALB CSGALNACT1 CSGALNACT1 HS2ST1 HS2ST1 EXTL3 EXTL3 FGFRL1 FGFRL1 JUN JUN FGA-2 FGA-2 SRC SRC AGRN AGRN EXT1 EXT1 CD4 CD4 FGFR1 FGFR1 B3GAT3 B3GAT3 NDST1 NDST1 THPO THPO B4GALT7 B4GALT7 SLC35B2 SLC35B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGAFibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it [...] (618 aa)
XYLT2Xylosyltransferase 2. (864 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (312 aa)
ALBSerum albumin. (608 aa)
CSGALNACT1Hexosyltransferase. (524 aa)
HS2ST1Uncharacterized protein. (356 aa)
EXTL3Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (919 aa)
FGFRL1Fibroblast growth factor receptor like 1. (526 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
FGA-2Fibrinogen C-terminal domain-containing protein. (206 aa)
SRCTyrosine-protein kinase. (538 aa)
AGRNAgrin. (2041 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
CD4CD4 molecule. (455 aa)
FGFR1Fibroblast growth factor receptor. (860 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (335 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
THPOThrombopoietin. (353 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (327 aa)
SLC35B2Solute carrier family 35 member B2. (437 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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