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BRD3 | Bromodomain containing 3. (722 aa) | ||||
CUL4A | Cullin 4A; Belongs to the cullin family. (764 aa) | ||||
TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (289 aa) | ||||
LIG4 | DNA ligase. (911 aa) | ||||
LOC102174738 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) | ||||
RNF4 | Ring finger protein 4. (196 aa) | ||||
FANCA | FA complementation group A. (1416 aa) | ||||
RBBP4-2 | WD_REPEATS_REGION domain-containing protein. (425 aa) | ||||
RAD50 | Zinc-hook domain-containing protein. (1332 aa) | ||||
VPS36 | Vacuolar protein sorting 36 homolog. (457 aa) | ||||
COPS9 | Uncharacterized protein. (57 aa) | ||||
SUB1 | SUB1 regulator of transcription. (127 aa) | ||||
RFC2 | Replication factor C subunit 2. (352 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (562 aa) | ||||
CAND1 | Cullin associated and neddylation dissociated 1. (1230 aa) | ||||
TIMELESS | Timeless circadian regulator. (1206 aa) | ||||
COPS3 | COP9 signalosome subunit 3. (423 aa) | ||||
TSSC4 | Tumor suppressing subtransferable candidate 4. (325 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
RMI1 | RecQ mediated genome instability 1. (624 aa) | ||||
COPS7A | COP9 signalosome subunit 7A. (277 aa) | ||||
CHD1L | Chromodomain helicase DNA binding protein 1 like. (893 aa) | ||||
BRD2 | Bromodomain containing 2. (803 aa) | ||||
INTS5 | Integrator complex subunit 5. (1018 aa) | ||||
RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa) | ||||
INTS8 | Integrator complex subunit 8. (1121 aa) | ||||
RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (395 aa) | ||||
WRNIP1 | WRN helicase interacting protein 1. (640 aa) | ||||
WRN | WRN RecQ like helicase. (1405 aa) | ||||
TRAIP | TRAF interacting protein. (471 aa) | ||||
FANCM | FA complementation group M. (2043 aa) | ||||
RAD51C | RAD51 paralog C. (371 aa) | ||||
TDP2 | Endo/exonuclease/phosphatase domain-containing protein. (330 aa) | ||||
SKP1 | S-phase kinase associated protein 1. (163 aa) | ||||
FANCB | Uncharacterized protein. (447 aa) | ||||
BRD9 | Bromodomain containing 9. (577 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
TONSL | Tonsoku like, DNA repair protein. (1371 aa) | ||||
RBBP4 | WD_REPEATS_REGION domain-containing protein. (426 aa) | ||||
GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) | ||||
ATAD5 | ATPase family AAA domain containing 5. (1894 aa) | ||||
RFC5 | Replication factor C subunit 5. (339 aa) | ||||
YJU2 | Uncharacterized protein. (320 aa) | ||||
PMS2 | PMS1 homolog 2, mismatch repair system component. (887 aa) | ||||
SLX4 | SLX4 structure-specific endonuclease subunit. (1752 aa) | ||||
INTS6 | Integrator complex subunit 6. (887 aa) | ||||
OTX1 | Orthodenticle homeobox 1. (355 aa) | ||||
POLD1 | DNA polymerase. (1115 aa) | ||||
BRD4 | Uncharacterized protein. (1336 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2. (1062 aa) | ||||
FAAP100 | FA core complex associated protein 100. (879 aa) | ||||
FANCL | RING-type domain-containing protein. (379 aa) | ||||
POLE3 | CBFD_NFYB_HMF domain-containing protein. (147 aa) | ||||
TAF1 | Transcription initiation factor TFIID subunit. (1882 aa) | ||||
DONSON | Downstream neighbor of SON. (561 aa) | ||||
RAD17 | RAD17 checkpoint clamp loader component. (709 aa) | ||||
RFC4 | Replication factor C subunit 4. (364 aa) | ||||
XRCC3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (341 aa) | ||||
TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1609 aa) | ||||
POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (603 aa) | ||||
RMI2 | Uncharacterized protein. (161 aa) | ||||
FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (568 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) | ||||
REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3134 aa) | ||||
DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1591 aa) | ||||
PNKP | Polynucleotide kinase 3'-phosphatase. (522 aa) | ||||
POLE4 | DNA polymerase epsilon 4, accessory subunit. (131 aa) | ||||
POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa) | ||||
FANCE | FA complementation group E. (444 aa) | ||||
HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) | ||||
ATRIP | ATR interacting protein. (791 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) | ||||
INTS3 | Integrator complex subunit 3. (1041 aa) | ||||
CUL1 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa) | ||||
SIRT6 | Sirtuin 6. (335 aa) | ||||
SUMO2 | Small ubiquitin-related modifier. (95 aa) | ||||
TOPBP1 | DNA topoisomerase II binding protein 1. (1521 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa) | ||||
COPS8 | COP9 signalosome subunit 8. (209 aa) | ||||
ETAA1 | ETAA1 activator of ATR kinase. (903 aa) | ||||
NELFB | Negative elongation factor complex member B. (817 aa) | ||||
LRR1 | Leucine rich repeat protein 1. (424 aa) |