Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP1 | CD68 | ENSCHIP00000011226 | ENSCHIP00000027336 | Uncharacterized protein; Belongs to the peptidase C14A family. | CD68 molecule. | 0.679 |
| CASP1 | IFNG | ENSCHIP00000011226 | ENSCHIP00000016152 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.772 |
| CASP1 | IL18 | ENSCHIP00000011226 | ENSCHIP00000023420 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.974 |
| CASP1 | IL1B | ENSCHIP00000011226 | ENSCHIP00000029274 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.990 |
| CASP1 | IL6 | ENSCHIP00000011226 | ENSCHIP00000009414 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.860 |
| CASP1 | NLRC4 | ENSCHIP00000011226 | ENSCHIP00000009511 | Uncharacterized protein; Belongs to the peptidase C14A family. | NLR family CARD domain containing 4. | 0.992 |
| CD68 | CASP1 | ENSCHIP00000027336 | ENSCHIP00000011226 | CD68 molecule. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.679 |
| CD68 | IFNG | ENSCHIP00000027336 | ENSCHIP00000016152 | CD68 molecule. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.837 |
| CD68 | IL18 | ENSCHIP00000027336 | ENSCHIP00000023420 | CD68 molecule. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.670 |
| CD68 | IL1B | ENSCHIP00000027336 | ENSCHIP00000029274 | CD68 molecule. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.892 |
| CD68 | IL6 | ENSCHIP00000027336 | ENSCHIP00000009414 | CD68 molecule. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.952 |
| ENSCHIP00000023849 | IFNG | ENSCHIP00000023849 | ENSCHIP00000016152 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.419 |
| ENSCHIP00000023849 | IL1B | ENSCHIP00000023849 | ENSCHIP00000029274 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.723 |
| ENSCHIP00000023849 | IL6 | ENSCHIP00000023849 | ENSCHIP00000009414 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.719 |
| GATM | GNMT | ENSCHIP00000017468 | ENSCHIP00000032360 | Glycine amidinotransferase. | Glycine N-methyltransferase. | 0.943 |
| GATM | SHMT1 | ENSCHIP00000017468 | ENSCHIP00000011211 | Glycine amidinotransferase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.938 |
| GATM | SHMT2 | ENSCHIP00000017468 | ENSCHIP00000001693 | Glycine amidinotransferase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.935 |
| GNMT | GATM | ENSCHIP00000032360 | ENSCHIP00000017468 | Glycine N-methyltransferase. | Glycine amidinotransferase. | 0.943 |
| GNMT | SHMT1 | ENSCHIP00000032360 | ENSCHIP00000011211 | Glycine N-methyltransferase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.962 |
| GNMT | SHMT2 | ENSCHIP00000032360 | ENSCHIP00000001693 | Glycine N-methyltransferase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.957 |
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