51 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108633916	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC102191748	Histone domain-containing protein. (136 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
	LOC102185882	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108633554	Histone domain-containing protein. (136 aa)
	LOC102182848	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108636012	Histone H3; Belongs to the histone H3 family. (136 aa)
	GDF9	Growth/differentiation factor 9; Required for ovarian folliculogenesis. (453 aa)
	H3-4	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC108634231	Histone H3; Belongs to the histone H3 family. (136 aa)
	CCDC174	Coiled-coil domain containing 174. (467 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	LOC102180554	Histone H3; Belongs to the histone H3 family. (136 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
	LOC106503499	Histone H3; Belongs to the histone H3 family. (136 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (581 aa)
	PRP6	Prolactin-related protein-6. (239 aa)
	LOC102171353	Histone H3; Belongs to the histone H3 family. (136 aa)
	ESR2	Uncharacterized protein. (527 aa)
	LOC102169981	Histone domain-containing protein. (136 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ROBO2	Roundabout guidance receptor 2. (1456 aa)
	LOC102170569	Uncharacterized protein. (211 aa)
	LOC102184390	Uncharacterized protein. (287 aa)
	KDM4A	Uncharacterized protein. (1067 aa)
	LOC102190477	Uncharacterized protein. (238 aa)
	ANKRD11	ANK_REP_REGION domain-containing protein. (2590 aa)
	ME3	Malic enzyme. (604 aa)
	BMP15	TGF_BETA_2 domain-containing protein. (403 aa)
	ALPK3	Alpha kinase 3. (1840 aa)
	LOC102178616	Uncharacterized protein. (265 aa)
	LOC108638107	Uncharacterized protein. (238 aa)
	GNRH1	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
	MTMR2	Myotubularin related protein 2. (643 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
	CGA	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (120 aa)
	RHO	Rhodopsin. (348 aa)
	ARID5B	AT-rich interaction domain 5B. (1187 aa)
	TRPM6	Transient receptor potential cation channel subfamily M member 6. (1971 aa)
	NOM1	Nucleolar protein with MIF4G domain 1. (835 aa)
	PRP1	Prolactin-related protein-1. (238 aa)
	LOC102189503	Histone H3; Belongs to the histone H3 family. (136 aa)
	CLSTN2	Calsyntenin 2. (955 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	FSHB	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa)
	LOC102180550	Uncharacterized protein. (237 aa)
	LOC102171116	Uncharacterized protein. (226 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (649 aa)
	ROBO2-2	Ig-like domain-containing protein. (128 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPK3	ANKRD11	ENSCHIP00000015192	ENSCHIP00000012413	Alpha kinase 3.	ANK_REP_REGION domain-containing protein.	0.481
ALPK3	CCDC174	ENSCHIP00000015192	ENSCHIP00000004127	Alpha kinase 3.	Coiled-coil domain containing 174.	0.834
ALPK3	CGA	ENSCHIP00000015192	ENSCHIP00000019012	Alpha kinase 3.	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.	0.654
ALPK3	CLSTN2	ENSCHIP00000015192	ENSCHIP00000025517	Alpha kinase 3.	Calsyntenin 2.	0.654
ALPK3	DLG1	ENSCHIP00000015192	ENSCHIP00000006322	Alpha kinase 3.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.712
ALPK3	KDM4A	ENSCHIP00000015192	ENSCHIP00000010775	Alpha kinase 3.	Uncharacterized protein.	0.436
ALPK3	MTMR2	ENSCHIP00000015192	ENSCHIP00000016893	Alpha kinase 3.	Myotubularin related protein 2.	0.530
ALPK3	NOM1	ENSCHIP00000015192	ENSCHIP00000021961	Alpha kinase 3.	Nucleolar protein with MIF4G domain 1.	0.692
ALPK3	TRPM6	ENSCHIP00000015192	ENSCHIP00000021760	Alpha kinase 3.	Transient receptor potential cation channel subfamily M member 6.	0.451
ANKRD11	ALPK3	ENSCHIP00000012413	ENSCHIP00000015192	ANK_REP_REGION domain-containing protein.	Alpha kinase 3.	0.481
ANKRD11	CCDC174	ENSCHIP00000012413	ENSCHIP00000004127	ANK_REP_REGION domain-containing protein.	Coiled-coil domain containing 174.	0.735
ANKRD11	CGA	ENSCHIP00000012413	ENSCHIP00000019012	ANK_REP_REGION domain-containing protein.	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.	0.658
ANKRD11	CLSTN2	ENSCHIP00000012413	ENSCHIP00000025517	ANK_REP_REGION domain-containing protein.	Calsyntenin 2.	0.445
ANKRD11	DLG1	ENSCHIP00000012413	ENSCHIP00000006322	ANK_REP_REGION domain-containing protein.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.597
ANKRD11	MTMR2	ENSCHIP00000012413	ENSCHIP00000016893	ANK_REP_REGION domain-containing protein.	Myotubularin related protein 2.	0.429
ANKRD11	NOM1	ENSCHIP00000012413	ENSCHIP00000021961	ANK_REP_REGION domain-containing protein.	Nucleolar protein with MIF4G domain 1.	0.573
ARID5B	CCDC174	ENSCHIP00000020747	ENSCHIP00000004127	AT-rich interaction domain 5B.	Coiled-coil domain containing 174.	0.694
ARID5B	NOM1	ENSCHIP00000020747	ENSCHIP00000021961	AT-rich interaction domain 5B.	Nucleolar protein with MIF4G domain 1.	0.508
BMP15	BMPR1B	ENSCHIP00000014000	ENSCHIP00000018336	TGF_BETA_2 domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.997
BMP15	ESR2	ENSCHIP00000014000	ENSCHIP00000008528	TGF_BETA_2 domain-containing protein.	Uncharacterized protein.	0.614