STRINGSTRING
PXDN PXDN RPA1 RPA1 POLE2 POLE2 RARG RARG GAPDH GAPDH CCNF CCNF CDK4 CDK4 POLD1 POLD1 MYCN MYCN MCM6 MCM6 WEE1 WEE1 POLA1 POLA1 CDT1 CDT1 POLE POLE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PXDNPeroxidasin. (1525 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
RARGRetinoic acid receptor gamma. (458 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
CCNFCyclin F; Belongs to the cyclin family. (789 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
POLD1DNA polymerase. (1115 aa)
MYCNMYCN proto-oncogene, bHLH transcription factor. (554 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
WEE1Wee1-like protein kinase. (645 aa)
POLA1DNA polymerase. (1468 aa)
CDT1Chromatin licensing and DNA replication factor 1. (637 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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