8 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HMOX1	Heme oxygenase 1. (288 aa)
	NFE2	Nuclear factor, erythroid 2. (374 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	SDHA	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
	LDH-A	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLDC	LDH-A	ENSCHIP00000025237	ENSCHIP00000019303	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.451
GLDC	PHGDH	ENSCHIP00000025237	ENSCHIP00000019405	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.856
GLDC	SDHA	ENSCHIP00000025237	ENSCHIP00000018522	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.652
GLDC	SHMT1	ENSCHIP00000025237	ENSCHIP00000011211	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.998
GLDC	SHMT2	ENSCHIP00000025237	ENSCHIP00000001693	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.998
HMOX1	LDH-A	ENSCHIP00000016460	ENSCHIP00000019303	Heme oxygenase 1.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.590
HMOX1	NFE2	ENSCHIP00000016460	ENSCHIP00000001678	Heme oxygenase 1.	Nuclear factor, erythroid 2.	0.631
LDH-A	GLDC	ENSCHIP00000019303	ENSCHIP00000025237	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.451
LDH-A	HMOX1	ENSCHIP00000019303	ENSCHIP00000016460	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	Heme oxygenase 1.	0.590
LDH-A	PHGDH	ENSCHIP00000019303	ENSCHIP00000019405	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.410
LDH-A	SDHA	ENSCHIP00000019303	ENSCHIP00000018522	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.700
NFE2	HMOX1	ENSCHIP00000001678	ENSCHIP00000016460	Nuclear factor, erythroid 2.	Heme oxygenase 1.	0.631
PHGDH	GLDC	ENSCHIP00000019405	ENSCHIP00000025237	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.856
PHGDH	LDH-A	ENSCHIP00000019405	ENSCHIP00000019303	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.410
PHGDH	SHMT1	ENSCHIP00000019405	ENSCHIP00000011211	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.925
PHGDH	SHMT2	ENSCHIP00000019405	ENSCHIP00000001693	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.961
SDHA	GLDC	ENSCHIP00000018522	ENSCHIP00000025237	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.652
SDHA	LDH-A	ENSCHIP00000018522	ENSCHIP00000019303	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.700
SDHA	SHMT1	ENSCHIP00000018522	ENSCHIP00000011211	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.567
SDHA	SHMT2	ENSCHIP00000018522	ENSCHIP00000001693	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.634