STRINGSTRING
SUMO4 SUMO4 RMI1 RMI1 VCL VCL MYC MYC SMC5 SMC5 RMI2 RMI2 GAPDH GAPDH RECQL RECQL SUMO2 SUMO2 RAD51 RAD51 TOP3A TOP3A FANCM FANCM SUMO3 SUMO3 ATRX ATRX SUMO1 SUMO1 RAD52 RAD52 TERT TERT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUMO4Small ubiquitin-related modifier. (95 aa)
RMI1RecQ mediated genome instability 1. (624 aa)
VCLVinculin. (1134 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
SMC5AAA_23 domain-containing protein. (1104 aa)
RMI2Uncharacterized protein. (161 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1002 aa)
FANCMFA complementation group M. (2043 aa)
SUMO3Small ubiquitin-related modifier. (104 aa)
ATRXATRX chromatin remodeler. (2105 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
RAD52RAD52 homolog, DNA repair protein. (416 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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