STRINGSTRING
HEY1 HEY1 IGFN1 IGFN1 APOE APOE COL4A1 COL4A1 GAPDH GAPDH NOTCH2 NOTCH2 LMNA LMNA PAX7 PAX7 PTGER4 PTGER4 PRKACB PRKACB COL1A2 COL1A2 GUSB GUSB COL4A2 COL4A2 COL5A3 COL5A3 MYOD1 MYOD1 CMKLR1 CMKLR1 CCND1 CCND1 COL5A2 COL5A2 UNC5B UNC5B CALCR CALCR HEYL HEYL ERBB3 ERBB3 DLL4 DLL4 COL8A1 COL8A1 PRKACA PRKACA NOTCH3 NOTCH3 COL6A2 COL6A2 FGF2 FGF2 COL6A3 COL6A3 ALB ALB CDK4 CDK4 NOTCH4 NOTCH4 JAG1 JAG1 COL1A1 COL1A1 MYOG MYOG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
IGFN1Uncharacterized protein. (1295 aa)
APOEApolipoprotein E. (326 aa)
COL4A1Collagen type IV alpha 1 chain. (1608 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
NOTCH2Notch receptor 2. (2471 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
PAX7Paired box 7. (503 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (513 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
COL1A2Collagen type I alpha 2 chain. (1128 aa)
GUSBUncharacterized protein. (659 aa)
COL4A2Collagen type IV alpha 2 chain. (1607 aa)
COL5A3Collagen type V alpha 3 chain. (1455 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
COL5A2Collagen type V alpha 2 chain. (1252 aa)
UNC5BUnc-5 netrin receptor B. (945 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (547 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1344 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
COL8A1Collagen type VIII alpha 1 chain. (745 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa)
NOTCH3Notch receptor 3. (2332 aa)
COL6A2Collagen type VI alpha 2 chain. (1027 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
COL6A3Collagen type VI alpha 3 chain. (3111 aa)
ALBSerum albumin. (608 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
NOTCH4Notch receptor 4. (1966 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
MYOGMyogenin. (224 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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