STRINGSTRING
FXR2 FXR2 ALKBH5 ALKBH5 NDUFA2 NDUFA2 TAF6 TAF6 WTAP WTAP NES NES METTL14 METTL14 CCNH CCNH GFAP GFAP YTHDF2 YTHDF2 GAPDH GAPDH ATP5PF ATP5PF LOC102189503 LOC102189503 ATP5MF ATP5MF CIRBP CIRBP LEP LEP COQ5 COQ5 ALB ALB NDUFA12 NDUFA12 CSDE1 CSDE1 FXR1 FXR1 CHRAC1 CHRAC1 UQCRC2 UQCRC2 PXDN PXDN NDUFV2 NDUFV2 MRPL50 MRPL50 NDUFA4 NDUFA4 NDUFA5 NDUFA5 EPS15 EPS15 NDUFB8 NDUFB8 POLR2E POLR2E NDUFB4 NDUFB4 COQ7 COQ7 ACTB ACTB SDHB SDHB ZFX ZFX ATP5PB ATP5PB MYO18A MYO18A MRPL51 MRPL51 NDUFAB1 NDUFAB1 COA5 COA5 INS INS MRPL53 MRPL53 MARCKS MARCKS NDUFA7 NDUFA7 FTO FTO RBM7 RBM7 TBP TBP NDUFA13 NDUFA13 YTHDC1 YTHDC1 MRPS18C MRPS18C FMR1 FMR1 NDUFA1 NDUFA1 CYTB CYTB ATP6 ATP6 COX1 COX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FXR2FMR1 autosomal homolog 2. (673 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
WTAPUncharacterized protein. (396 aa)
NESNestin; Belongs to the intermediate filament family. (1606 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (428 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (582 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
ATP5MFUncharacterized protein. (104 aa)
CIRBPCold inducible RNA binding protein. (171 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa)
ALBSerum albumin. (608 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
CSDE1Cold shock domain containing E1. (844 aa)
FXR1FMR1 autosomal homolog 1. (648 aa)
CHRAC1CBFD_NFYB_HMF domain-containing protein. (130 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
PXDNPeroxidasin. (1525 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
MRPL50Mitochondrial ribosomal protein L50. (159 aa)
NDUFA4NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex 4. (82 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (108 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (910 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa)
ACTBUncharacterized protein. (375 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
ZFXUncharacterized protein. (800 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2049 aa)
MRPL51Mitochondrial ribosomal protein L51. (128 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
COA5Cytochrome c oxidase assembly factor 5. (79 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
MRPL53Uncharacterized protein. (112 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (333 aa)
NDUFA7Uncharacterized protein. (126 aa)
FTOFat mass and obesity associated protein. (505 aa)
RBM7RRM domain-containing protein. (262 aa)
TBPUncharacterized protein. (327 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
YTHDC1YTH domain containing 1. (698 aa)
MRPS18CUncharacterized protein. (143 aa)
FMR1Fragile X mental retardation 1. (632 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (70 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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