STRINGSTRING
PTGS2 PTGS2 XBP1 XBP1 WARS1 WARS1 ABCC5 ABCC5 SLC19A1 SLC19A1 HSPA5 HSPA5 ABCG2 ABCG2 PLK3 PLK3 SHMT2 SHMT2 FPGS FPGS PSPH PSPH ABCC4 ABCC4 GGH GGH ABCC1 ABCC1 EIF2S1 EIF2S1 ACTB ACTB ATF4 ATF4 ATF3 ATF3 AARS1 AARS1 PXDN PXDN DHFR DHFR PHGDH PHGDH ATF6 ATF6 AARS2 AARS2 ALDH1L2 ALDH1L2 NFKB2 NFKB2 ABCB1 ABCB1 TRIB3 TRIB3 SLC46A1 SLC46A1 EPRS1 EPRS1 MTHFD2 MTHFD2 GAPDH GAPDH PSAT1 PSAT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
XBP1BZIP domain-containing protein. (261 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa)
ABCC5ATP binding cassette subfamily C member 5. (1445 aa)
SLC19A1Solute carrier family 19 member 1. (508 aa)
HSPA5Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family. (655 aa)
ABCG2Breast cancer resistance protein. (658 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (585 aa)
PSPHPhosphoserine phosphatase. (225 aa)
ABCC4Uncharacterized protein. (1323 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
ABCC1ATP binding cassette subfamily C member 1. (1595 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ACTBUncharacterized protein. (375 aa)
ATF4Activating transcription factor 4. (352 aa)
ATF3Activating transcription factor 3. (181 aa)
AARS1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
PXDNPeroxidasin. (1525 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
ATF6Activating transcription factor 6. (664 aa)
AARS2Alanyl-tRNA synthetase 2, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (983 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
ABCB1Uncharacterized protein. (1242 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
EPRS1Glutamyl-prolyl-tRNA synthetase. (1518 aa)
MTHFD2Uncharacterized protein. (352 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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