STRINGSTRING
WNT8A WNT8A WNT3 WNT3 HEY2 HEY2 ADAMTS4 ADAMTS4 CTNNB1 CTNNB1 TBX5 TBX5 APLNR APLNR HES3 HES3 ISL1 ISL1 GAPDH GAPDH WNT11 WNT11 BMP4 BMP4 AXIN2 AXIN2 RSPO2 RSPO2 FLT1 FLT1 FOXF1 FOXF1 GATA6 GATA6 PDGFRA PDGFRA KDR KDR DLL3 DLL3 INS INS RSPO3 RSPO3 HOXA10 HOXA10 DKK1 DKK1 PXDN PXDN MEF2C MEF2C IL11 IL11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (872 aa)
CTNNB1Catenin beta 1. (781 aa)
TBX5T-box transcription factor 5. (594 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
HES3Hes family bHLH transcription factor 3. (178 aa)
ISL1ISL LIM homeobox 1. (349 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
AXIN2Axin 2. (844 aa)
RSPO2R-spondin 2. (243 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
FOXF1Forkhead box F1. (391 aa)
GATA6GATA binding protein 6. (592 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
DLL3Delta like canonical Notch ligand 3. (595 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
RSPO3R-spondin 3. (303 aa)
HOXA10Homeobox A10. (413 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (262 aa)
PXDNPeroxidasin. (1525 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
IL11Interleukin 11. (191 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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