STRINGSTRING
KDM5B KDM5B PSPH PSPH CASP3 CASP3 ME3 ME3 PHF2 PHF2 PXDN PXDN KDM4B KDM4B PHGDH PHGDH PSAT1 PSAT1 BRCA1 BRCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KDM5BLysine demethylase 5B. (1539 aa)
PSPHPhosphoserine phosphatase. (225 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
ME3Malic enzyme. (604 aa)
PHF2PHD finger protein 2. (1100 aa)
PXDNPeroxidasin. (1525 aa)
KDM4BLysine demethylase 4B. (1070 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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