29 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	CD19	CD19 molecule. (561 aa)
	CCL22	C-C motif chemokine. (93 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	SLC1A5	Amino acid transporter. (530 aa)
	SLC1A7	Amino acid transporter. (574 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
	ATF6	Activating transcription factor 6. (664 aa)
	SLC1A1	Amino acid transporter. (534 aa)
	CHAC1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (260 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	ATF4	Activating transcription factor 4. (352 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	ACTB	Uncharacterized protein. (375 aa)
	AICDA	Activation induced cytidine deaminase. (199 aa)
	TMEM176B	Transmembrane protein 176B. (265 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SLC1A6	Amino acid transporter. (564 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (125 aa)
	CD93	CD93 molecule. (649 aa)
	PSPH	Phosphoserine phosphatase. (225 aa)
	CD38	Uncharacterized protein. (277 aa)
	IL5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (129 aa)
	SLC1A2	Amino acid transporter. (578 aa)
	SLC6A9	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (698 aa)
	SLC1A4	Solute carrier family 1 member 4. (527 aa)
	PDAP1	PDGFA associated protein 1. (182 aa)
	XBP1	BZIP domain-containing protein. (261 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	AICDA	ENSCHIP00000011080	ENSCHIP00000009604	Uncharacterized protein.	Activation induced cytidine deaminase.	0.434
ACTB	ATF4	ENSCHIP00000011080	ENSCHIP00000013483	Uncharacterized protein.	Activating transcription factor 4.	0.683
ACTB	ATF6	ENSCHIP00000011080	ENSCHIP00000019493	Uncharacterized protein.	Activating transcription factor 6.	0.774
ACTB	CD19	ENSCHIP00000011080	ENSCHIP00000027580	Uncharacterized protein.	CD19 molecule.	0.754
ACTB	CD38	ENSCHIP00000011080	ENSCHIP00000001838	Uncharacterized protein.	Uncharacterized protein.	0.544
ACTB	ESR1	ENSCHIP00000011080	ENSCHIP00000012243	Uncharacterized protein.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.859
ACTB	GAPDH	ENSCHIP00000011080	ENSCHIP00000025974	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
ACTB	IL4	ENSCHIP00000011080	ENSCHIP00000020527	Uncharacterized protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.834
ACTB	IL5	ENSCHIP00000011080	ENSCHIP00000001075	Uncharacterized protein.	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	0.680
ACTB	SLC1A1	ENSCHIP00000011080	ENSCHIP00000019349	Uncharacterized protein.	Amino acid transporter.	0.497
ACTB	SLC1A2	ENSCHIP00000011080	ENSCHIP00000033328	Uncharacterized protein.	Amino acid transporter.	0.474
ACTB	SLC1A3	ENSCHIP00000011080	ENSCHIP00000017001	Uncharacterized protein.	Amino acid transporter.	0.472
ACTB	SLC1A5	ENSCHIP00000011080	ENSCHIP00000023350	Uncharacterized protein.	Amino acid transporter.	0.515
ACTB	SLC1A6	ENSCHIP00000011080	ENSCHIP00000005613	Uncharacterized protein.	Amino acid transporter.	0.495
ACTB	SLC1A7	ENSCHIP00000011080	ENSCHIP00000021080	Uncharacterized protein.	Amino acid transporter.	0.495
ACTB	TGFB1	ENSCHIP00000011080	ENSCHIP00000008885	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.831
ACTB	XBP1	ENSCHIP00000011080	ENSCHIP00000027960	Uncharacterized protein.	BZIP domain-containing protein.	0.770
AICDA	ACTB	ENSCHIP00000009604	ENSCHIP00000011080	Activation induced cytidine deaminase.	Uncharacterized protein.	0.434
AICDA	BATF	ENSCHIP00000009604	ENSCHIP00000005160	Activation induced cytidine deaminase.	Basic leucine zipper ATF-like transcription factor.	0.681
AICDA	CD19	ENSCHIP00000009604	ENSCHIP00000027580	Activation induced cytidine deaminase.	CD19 molecule.	0.801