27 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TACSTD2	Tumor associated calcium signal transducer 2. (315 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	ALK	Tyrosine-protein kinase receptor. (1309 aa)
	HYAL2	Hyaluronidase. (476 aa)
	HYAL4	Hyaluronidase. (481 aa)
	KRT5	Keratin 5; Belongs to the intermediate filament family. (561 aa)
	HOXB13	Homeobox B13. (285 aa)
	KRT4	Keratin 4; Belongs to the intermediate filament family. (555 aa)
	S100A4	Protein S100; Belongs to the S-100 family. (101 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	RSPO1	Ovarian R-spondin member 1. (262 aa)
	HYAL1	Hyaluronidase. (450 aa)
	AR	Androgen receptor. (891 aa)
	VIM	Vimentin; Belongs to the intermediate filament family. (471 aa)
	LOC102168417	Hyaluronidase. (475 aa)
	LOC100860748	Hyaluronidase. (551 aa)
	KRT15	Keratin 15; Belongs to the intermediate filament family. (453 aa)
	KRT8	Keratin 8; Belongs to the intermediate filament family. (484 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	HYAL3	Hyaluronidase. (419 aa)
	BMI1	RING-type domain-containing protein. (437 aa)
	SPINK5	Serine peptidase inhibitor, Kazal type 5. (1091 aa)
	CD24	Uncharacterized protein. (78 aa)
	LOC102168691	Hyaluronidase. (550 aa)
	KRT14	Keratin 14; Belongs to the intermediate filament family. (514 aa)
	GATA2	GATA binding protein 2. (480 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALK	NOG	ENSCHIP00000004260	ENSCHIP00000005264	Tyrosine-protein kinase receptor.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.455
ALK	TGFB1	ENSCHIP00000004260	ENSCHIP00000008885	Tyrosine-protein kinase receptor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.593
AR	GATA2	ENSCHIP00000024342	ENSCHIP00000013299	Androgen receptor.	GATA binding protein 2.	0.439
AR	HOXB13	ENSCHIP00000024342	ENSCHIP00000032940	Androgen receptor.	Homeobox B13.	0.662
AR	KRT5	ENSCHIP00000024342	ENSCHIP00000000926	Androgen receptor.	Keratin 5; Belongs to the intermediate filament family.	0.576
AR	KRT8	ENSCHIP00000024342	ENSCHIP00000019928	Androgen receptor.	Keratin 8; Belongs to the intermediate filament family.	0.597
AR	VIM	ENSCHIP00000024342	ENSCHIP00000022577	Androgen receptor.	Vimentin; Belongs to the intermediate filament family.	0.424
BMI1	CD24	ENSCHIP00000016491	ENSCHIP00000013924	RING-type domain-containing protein.	Uncharacterized protein.	0.700
BMI1	LGR5	ENSCHIP00000016491	ENSCHIP00000019084	RING-type domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.908
BMI1	NOG	ENSCHIP00000016491	ENSCHIP00000005264	RING-type domain-containing protein.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.471
CD24	BMI1	ENSCHIP00000013924	ENSCHIP00000016491	Uncharacterized protein.	RING-type domain-containing protein.	0.700
CD24	HYAL1	ENSCHIP00000013924	ENSCHIP00000027713	Uncharacterized protein.	Hyaluronidase.	0.675
CD24	HYAL2	ENSCHIP00000013924	ENSCHIP00000003847	Uncharacterized protein.	Hyaluronidase.	0.665
CD24	HYAL3	ENSCHIP00000013924	ENSCHIP00000016919	Uncharacterized protein.	Hyaluronidase.	0.657
CD24	HYAL4	ENSCHIP00000013924	ENSCHIP00000001850	Uncharacterized protein.	Hyaluronidase.	0.657
CD24	KRT14	ENSCHIP00000013924	ENSCHIP00000013319	Uncharacterized protein.	Keratin 14; Belongs to the intermediate filament family.	0.548
CD24	KRT5	ENSCHIP00000013924	ENSCHIP00000000926	Uncharacterized protein.	Keratin 5; Belongs to the intermediate filament family.	0.535
CD24	KRT8	ENSCHIP00000013924	ENSCHIP00000019928	Uncharacterized protein.	Keratin 8; Belongs to the intermediate filament family.	0.651
CD24	LGR5	ENSCHIP00000013924	ENSCHIP00000019084	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.740
CD24	LOC100860748	ENSCHIP00000013924	ENSCHIP00000021797	Uncharacterized protein.	Hyaluronidase.	0.677